HitPredict

Interactor 1: ERLN2 (O94905)
Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2)
Gene: ERLIN2

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	21343306, 33141564, 16196087
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 339 Hs			1 685
+	Hs
		266095 ERLN1_HUMAN (20-333): 1.91e-100: 301: 78.03		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475364 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476542 STML2_HUMAN (20-319): 7.67e-59: 195: 14.24		UBC_HUMAN (1-685): 0: 846: 100.00
+	At
		1092006 PHB7_ARATH (6-259): 2.85e-58: 191: 11.36		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	Hs
		266140 ERLN1_HUMAN (20-333): 1.91e-100: 301: 78.03		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Hs
		266092 ERLN1_HUMAN (20-333): 1.91e-100: 301: 78.03		ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69