HitPredict

Interactor 1: ERLN2 (O94905)
Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2)
Gene: ERLIN2

Interactor 2: RHOA (P61586)
Transforming protein RhoA (EC 3.6.5.2) (Rho cDNA clone 12) (h12)
Gene: RHOA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 339 Hs			1 193
+	Hs
		266137 ERLN1_HUMAN (20-333): 1.91e-100: 301: 78.03		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		266141 ERLN1_HUMAN (20-333): 1.91e-100: 301: 78.03		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		266135 ERLN1_HUMAN (20-333): 1.91e-100: 301: 78.03		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		266139 ERLN1_HUMAN (20-333): 1.91e-100: 301: 78.03		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		646160 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RHOA_HUMAN (1-193): 1.4e-80: 239: 100.00
+	Hs
		646166 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RAC1_HUMAN (1-193): 8.86e-80: 237: 57.22
+	Hs
		436164 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RHOC_HUMAN (1-193): 3.04e-78: 233: 91.71
+	Hs
		646171 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40
+	Hs
		646157 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		CDC42_HUMAN (1-193): 5.51e-77: 230: 52.33
+	Hs
		545212 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RAC2_HUMAN (1-193): 3.9e-76: 228: 53.61
+	Hs
		646156 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RAC3_HUMAN (1-179): 4.85e-74: 223: 57.54
+	Hs
		646164 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RHOB_HUMAN (1-191): 1.62e-73: 221: 83.94
+	Hs
		120306 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RHOD_HUMAN (7-182): 1.68e-69: 212: 53.98
+	Hs
		951448 STML2_HUMAN (20-319): 7.67e-59: 195: 14.24		RHOG_HUMAN (1-193): 2.83e-77: 231: 54.40