Interactor 1: ERLN2 (O94905)
Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2)
Gene: ERLIN2

Interactor 2: SCAP (Q12770)
Sterol regulatory element-binding protein cleavage-activating protein (SCAP) (SREBP cleavage-activating protein)
Gene: SCAP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 22690709, 24217618
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0008203 - cholesterol metabolic process
GO:0032933 - SREBP signaling pathway
GO:0045540 - regulation of cholesterol biosynthetic process
and 1 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 339
Hs

1 1279
+ Hs
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Last updated: 15 Jul 2024