HitPredict

Interactor 1: ERLN2 (O94905)
Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2)
Gene: ERLIN2

Interactor 2: FAF2 (Q96CS3)
FAS-associated factor 2 (UBX domain-containing protein 3B) (UBX domain-containing protein 8)
Gene: FAF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	22119785, 34406391
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0031625 - ubiquitin protein ligase binding GO:0036503 - ERAD pathway
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 339 Hs			1 445
+	Hs
		266225 ERLN1_HUMAN (20-333): 1.91e-100: 301: 78.03		FAF2_HUMAN (1-445): 1.33e-143: 419: 100.00
+	Hs
		646261 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		FAF2_HUMAN (1-445): 1.33e-143: 419: 100.00
+	Hs
		300007 ERLN2_HUMAN (1-339): 5.38e-116: 341: 100.00		FAF1_HUMAN (112-440): 5.62e-83: 269: 24.79
+	Hs
		1356207 STML2_HUMAN (20-319): 7.67e-59: 195: 14.24		FAF1_HUMAN (112-440): 5.62e-83: 269: 24.79