HitPredict

Interactor 1: PRP6 (O94906)
Pre-mRNA-processing factor 6 (Androgen receptor N-terminal domain-transactivating protein 1) (ANT-1) (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein)
Gene: PRPF6

Interactor 2: PRP6 (O94906)
Pre-mRNA-processing factor 6 (Androgen receptor N-terminal domain-transactivating protein 1) (ANT-1) (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein)
Gene: PRPF6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.800

The method score is based on:

Property Details
Experiments 10848612, 16723661
Identification Methods two hybrid, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains TPR_16~TPR_16, TPR_16~TPR_19, TPR_19~TPR_19
Common GO terms GO:0000244 - spliceosomal tri-snRNP complex assembly
GO:0000245 - spliceosomal complex assembly
GO:0000375 - RNA splicing, via transesterification reactions
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
and 16 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 941
Hs

1 941
+ Hs
+ Sp
+ Hs
+ Sp
+ Hs
+ At
+ Dm
+ Sc
+ Sc
+ Hs
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024