HitPredict

Interactor 1: PRP6 (O94906)
Pre-mRNA-processing factor 6 (Androgen receptor N-terminal domain-transactivating protein 1) (ANT-1) (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein)
Gene: PRPF6

Interactor 2: ESR1 (P03372)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23403292
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016020 - membrane GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 941 Hs			1 595
+	Hs
		370376 CRNL1_HUMAN (521-932): 8.54e-41: 164: 12.50		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		300039 PRP6_HUMAN (1-941): 0: 610: 100.00		ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16
+	Hs
		369613 RRP5_HUMAN (474-761): 1.34e-26: 120: 14.09		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		369839 CTR9_HUMAN (126-536): 3.3e-16: 85.7: 10.12		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		370484 SYF1_HUMAN (109-527): 1.77e-12: 73.4: 13.78		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		174531 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		ESR1_HUMAN (1-595): 0: 599: 100.00
+	Hs
		1190470 TT21B_HUMAN (258-935): 6.29e-42: 168: 13.15		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88
+	Hs
		1057989 RRP5_HUMAN (474-761): 1.34e-26: 120: 14.09		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88
+	Hs
		377572 TTC28_HUMAN (441-940): 3.1e-38: 157: 7.45		GCR_HUMAN (5-557): 4.67e-109: 346: 22.51
+	Hs
		1160955 CTR9_HUMAN (126-536): 3.3e-16: 85.7: 10.12		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88
+	Hs
		1269676 SYF1_HUMAN (109-527): 1.77e-12: 73.4: 13.78		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88
+	Hs
		175077 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		ESR2_HUMAN (26-582): 8.89e-136: 408: 45.88
+	Hs
		611462 PRP39_HUMAN (425-927): 1.16e-23: 109: 15.92		NR4A1_HUMAN (64-549): 2.81e-105: 331: 24.54
+	Mm
		1142644 CTR9_MOUSE (126-536): 5.01e-16: 85.3: 10.12		ERR2_MOUSE (92-547): 6.98e-113: 345: 34.42
+	Mm
		1142687 OGT1_MOUSE (120-352): 4.66e-10: 65.7: 11.39		ERR2_MOUSE (92-547): 6.98e-113: 345: 34.42
+	Hs
		487741 CRNL1_HUMAN (521-932): 8.54e-41: 164: 12.50		ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16
+	Hs
		487530 CTR9_HUMAN (126-536): 3.3e-16: 85.7: 10.12		ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16
+	Hs
		487776 SYF1_HUMAN (109-527): 1.77e-12: 73.4: 13.78		ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16
+	Hs
		174572 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		ANDR_HUMAN (172-455): 8.95e-37: 148: 30.16