HitPredict

Interactor 1: PRP6 (O94906)
Pre-mRNA-processing factor 6 (Androgen receptor N-terminal domain-transactivating protein 1) (ANT-1) (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein)
Gene: PRPF6

Interactor 2: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	10848612, 36244648
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 941 Hs			1 648
+	Hs
		300040 PRP6_HUMAN (1-941): 0: 610: 100.00		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	Hs
		300031 PRP6_HUMAN (1-941): 0: 610: 100.00		FYN_HUMAN (337-607): 2.33e-103: 326: 34.55
+	Hs
		374836 CRNL1_HUMAN (521-932): 8.54e-41: 164: 12.50		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		374238 RRP5_HUMAN (474-761): 1.34e-26: 120: 14.09		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		374469 PRP39_HUMAN (425-927): 1.16e-23: 109: 15.92		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		374914 SYF1_HUMAN (109-527): 1.77e-12: 73.4: 13.78		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		542879 RRP5_HUMAN (474-761): 1.34e-26: 120: 14.09		BRAF_HUMAN (39-647): 1.29e-170: 507: 55.88
+	Hs
		174558 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		YES_HUMAN (329-607): 1.22e-105: 332: 33.92
+	Hs
		174981 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		KSR2_HUMAN (332-623): 6.72e-43: 168: 34.43