HitPredict

Interactor 1: RHBT3 (O94955)
Rho-related BTB domain-containing protein 3 (EC 3.6.1.-)
Gene: RHOBTB3

Interactor 2: RHOC (P08134)
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Gene: RHOC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0005634 - nucleus GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 611 Hs			1 193
+	Hs
		893858 CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85		RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71
+	Mm
		892717 CDC42_MOUSE (31-209): 2.37e-74: 237: 18.85		RAC1_MOUSE (1-193): 7.23e-81: 240: 57.22
+	Hs
		893879 CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85		RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22
+	Hs
		436229 CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85		RHOC_HUMAN (1-193): 5.13e-80: 238: 100.00
+	Hs
		893897 CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85		RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92
+	Hs
		893846 CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85		CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30
+	Hs
		545294 CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85		RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12
+	Hs
		893871 CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85		RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82
+	Hs
		901066 KLH20_HUMAN (354-610): 1.47e-64: 224: 16.18		RHOA_HUMAN (1-193): 2.98e-81: 241: 91.71
+	Hs
		892296 CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85		RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54
+	Mm
		925823 RAC1_MOUSE (31-206): 5.82e-66: 215: 20.75		RHOA_MOUSE (1-193): 7.11e-82: 242: 92.23
+	Hs
		925169 RAC1_HUMAN (31-206): 5.82e-66: 215: 20.75		RAC1_HUMAN (1-193): 7.23e-81: 240: 57.22
+	Hs
		925187 RAC1_HUMAN (31-206): 5.82e-66: 215: 20.75		RHOG_HUMAN (1-193): 3.54e-78: 233: 54.92
+	Hs
		545309 RAC1_HUMAN (31-206): 5.82e-66: 215: 20.75		RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12
+	Hs
		893868 RB11A_HUMAN (25-238): 3.27e-65: 214: 13.33		CDC42_HUMAN (1-193): 7.44e-78: 232: 51.30
+	Hs
		545305 RB11A_HUMAN (25-238): 3.27e-65: 214: 13.33		RAC2_HUMAN (1-193): 2.27e-77: 231: 54.12
+	Hs
		915587 RAC1_HUMAN (31-206): 5.82e-66: 215: 20.75		RHOB_HUMAN (1-191): 3.6e-77: 230: 84.82
+	Hs
		892307 RAC1_HUMAN (31-206): 5.82e-66: 215: 20.75		RAC3_HUMAN (1-179): 9.72e-75: 224: 57.54