HitPredict

Interactor 1: RHBT3 (O94955)
Rho-related BTB domain-containing protein 3 (EC 3.6.1.-)
Gene: RHOBTB3

Interactor 2: IL1R2 (P27930)
Interleukin-1 receptor type 2 (IL-1R-2) (IL-1RT-2) (IL-1RT2) (CD121 antigen-like family member B) (CDw121b) (IL-1 type II receptor) (Interleukin-1 receptor beta) (IL-1R-beta) (Interleukin-1 receptor type II) (CD antigen CD121b) [Cleaved into: Interleukin-1 receptor type 2, membrane form (mIL-1R2) (mIL-1RII); Interleukin-1 receptor type 2, soluble form (sIL-1R2) (sIL-1RII)]
Gene: IL1R2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 611 Hs			1 398
+	Hs
		49981 RHBT1_HUMAN (31-611): 3.3e-116: 363: 18.45		PXDNL_HUMAN (2-225): 6.69e-34: 135: 17.86
+	Hs
		925644 RAC1_HUMAN (31-206): 5.82e-66: 215: 20.75		IL1AP_HUMAN (7-352): 4.61e-88: 279: 20.94
+	Hs
		309818 RAC1_HUMAN (31-206): 5.82e-66: 215: 20.75		I18RA_HUMAN (53-366): 3.7e-74: 243: 23.08
+	Hs
		609618 KLH20_HUMAN (354-610): 1.47e-64: 224: 16.18		FGFR3_HUMAN (7-383): 2.88e-58: 205: 16.75
+	Hs
		540389 RAC1_HUMAN (31-206): 5.82e-66: 215: 20.75		IL1R1_HUMAN (1-395): 4.82e-57: 197: 22.87
+	Hs
		894276 CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85		PXDN_HUMAN (234-398): 3.1e-24: 107: 12.65
+	Hs
		894644 CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85		ROBO1_HUMAN (5-384): 4.16e-20: 94.7: 10.27
+	Hs
		925776 RAC1_HUMAN (31-206): 5.82e-66: 215: 20.75		ROBO1_HUMAN (5-384): 4.16e-20: 94.7: 10.27
+	Hs
		914506 RB11A_HUMAN (25-238): 3.27e-65: 214: 13.33		ROBO1_HUMAN (5-384): 4.16e-20: 94.7: 10.27
+	Hs
		894044 CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85		MYLK_HUMAN (169-343): 1.5e-12: 71.5: 12.00
+	Hs
		901110 RHOA_HUMAN (29-204): 6.83e-65: 213: 17.55		ROBO1_HUMAN (5-384): 4.16e-20: 94.7: 10.27
+	Ce
		136794 CDC42_CAEEL (31-209): 3.91e-74: 237: 22.51		UNC89_CAEEL (5-149): 6.26e-11: 66.5: 13.51
+	Ce
		136793 RAC1_CAEEL (31-205): 3.92e-64: 211: 23.00		UNC89_CAEEL (5-149): 6.26e-11: 66.5: 13.51
+	Hs
		914253 RB11A_HUMAN (25-238): 3.27e-65: 214: 13.33		TITIN_HUMAN (5-395): 4.64e-09: 60.8: 8.19
+	Ce
		104464 G5EBV3_CAEEL (34-213): 9.27e-32: 123: 21.35		UNC89_CAEEL (5-149): 6.26e-11: 66.5: 13.51