HitPredict

Interactor 1: RHBT3 (O94955)
Rho-related BTB domain-containing protein 3 (EC 3.6.1.-)
Gene: RHOBTB3

Interactor 2: NRG1 (Q02297)
Pro-neuregulin-1, membrane-bound isoform (Pro-NRG1) [Cleaved into: Neuregulin-1 (Acetylcholine receptor-inducing activity) (ARIA) (Breast cancer cell differentiation factor p45) (Glial growth factor) (Heregulin) (HRG) (Neu differentiation factor) (Sensory and motor neuron-derived factor)]
Gene: NRG1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 611 Hs			1 640
+	Hs
		894276 CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85		PXDN_HUMAN (1-581): 4.95e-54: 202: 13.11
+	Hs
		894644 CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85		ROBO1_HUMAN (27-497): 1.45e-47: 182: 11.44
+	Hs
		925776 RAC1_HUMAN (31-206): 5.82e-66: 215: 20.75		ROBO1_HUMAN (27-497): 1.45e-47: 182: 11.44
+	Hs
		914506 RB11A_HUMAN (25-238): 3.27e-65: 214: 13.33		ROBO1_HUMAN (27-497): 1.45e-47: 182: 11.44
+	Hs
		901110 RHOA_HUMAN (29-204): 6.83e-65: 213: 17.55		ROBO1_HUMAN (27-497): 1.45e-47: 182: 11.44
+	Hs
		894044 CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85		MYLK_HUMAN (14-129): 9.86e-21: 99.8: 21.37
+	Hs
		489933 CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85		PTPRF_HUMAN (3-576): 1.34e-19: 95.9: 12.20
+	Hs
		894259 CDC42_HUMAN (31-209): 2.37e-74: 237: 18.85		PALLD_HUMAN (36-243): 6.76e-16: 83.8: 12.80
+	Hs
		489942 RAC1_HUMAN (31-206): 5.82e-66: 215: 20.75		PTPRF_HUMAN (3-576): 1.34e-19: 95.9: 12.20
+	Hs
		489932 RAC3_HUMAN (31-196): 1.39e-65: 214: 19.10		PTPRF_HUMAN (3-576): 1.34e-19: 95.9: 12.20
+	Hs
		489936 RHOA_HUMAN (29-204): 6.83e-65: 213: 17.55		PTPRF_HUMAN (3-576): 1.34e-19: 95.9: 12.20
+	Ce
		136794 CDC42_CAEEL (31-209): 3.91e-74: 237: 22.51		UNC89_CAEEL (36-141): 8.69e-12: 71.1: 15.09
+	Hs
		489896 RAC2_HUMAN (31-205): 2.83e-64: 211: 19.25		PTPRF_HUMAN (3-576): 1.34e-19: 95.9: 12.20
+	Ce
		136793 RAC1_CAEEL (31-205): 3.92e-64: 211: 23.00		UNC89_CAEEL (36-141): 8.69e-12: 71.1: 15.09
+	Hs
		914253 RB11A_HUMAN (25-238): 3.27e-65: 214: 13.33		TITIN_HUMAN (19-217): 1.22e-10: 67.4: 11.33
+	Ce
		104464 G5EBV3_CAEEL (34-213): 9.27e-32: 123: 21.35		UNC89_CAEEL (36-141): 8.69e-12: 71.1: 15.09