HitPredict

Interactor 1: MTCL2 (O94964)
Microtubule cross-linking factor 2 (SOGA family member 1) (Suppressor of glucose by autophagy) (Suppressor of glucose, autophagy-associated protein 1) [Cleaved into: N-terminal form; C-terminal 80 kDa form (80-kDa SOGA fragment)]
Gene: MTCL2

Interactor 2: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	34732716
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1661 Hs			1 317
+	Hs
		148522 CTRO_HUMAN (184-1015): 5.73e-38: 158: 13.74		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		725110 MYH10_HUMAN (858-1416): 2.04e-15: 84.7: 10.38		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		317221 PCNT_HUMAN (480-1344): 1.16e-10: 69.2: 11.32		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		1061259 NUMA1_HUMAN (2-1342): 1.76e-42: 173: 10.54		TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75
+	Hs
		551635 DESP_HUMAN (382-1142): 2.81e-09: 64.5: 16.26		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		331814 NUMA1_HUMAN (2-1342): 1.76e-42: 173: 10.54		NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71
+	Hs
		148725 CTRO_HUMAN (184-1015): 5.73e-38: 158: 13.74		SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68
+	Mm
		93555 DESP_MOUSE (214-861): 6.71e-11: 69.9: 16.55		SOX17_MOUSE (7-290): 2.02e-35: 134: 27.59
+	Hs
		1300969 DAPLE_HUMAN (217-1134): 1.43e-11: 72.2: 18.97		CIC_HUMAN (3-272): 8.9e-33: 130: 22.26
+	Hs
		551812 DESP_HUMAN (382-1142): 2.81e-09: 64.5: 16.26		CIC_HUMAN (3-272): 8.9e-33: 130: 22.26
+	Hs
		331895 DAPLE_HUMAN (217-1134): 1.43e-11: 72.2: 18.97		NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71