HitPredict

Interactor 1: MTCL2 (O94964)
Microtubule cross-linking factor 2 (SOGA family member 1) (Suppressor of glucose by autophagy) (Suppressor of glucose, autophagy-associated protein 1) [Cleaved into: N-terminal form; C-terminal 80 kDa form (80-kDa SOGA fragment)]
Gene: MTCL2

Interactor 2: DYL1 (P63167)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN)
Gene: DYNLL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	26496610, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005874 - microtubule
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1661 Hs			1 89
+	Hs
		301312 MTCL2_HUMAN (1-1661): 5.75e-170: 560: 100.00		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26
+	Hs
		928541 MTCL1_HUMAN (1-1119): 7.77e-57: 220: 33.25		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		1291340 MTCL1_HUMAN (1-1119): 7.77e-57: 220: 33.25		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26
+	Hs
		928303 NUMA1_HUMAN (2-1342): 1.76e-42: 173: 10.54		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		148656 CTRO_HUMAN (184-1015): 5.73e-38: 158: 13.74		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		317227 PCNT_HUMAN (480-1344): 1.16e-10: 69.2: 11.32		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		317324 PCNT_HUMAN (480-1344): 1.16e-10: 69.2: 11.32		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26
+	Hs
		551662 DESP_HUMAN (382-1142): 2.81e-09: 64.5: 16.26		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00