HitPredict

Interactor 1: MTCL2 (O94964)
Microtubule cross-linking factor 2 (SOGA family member 1) (Suppressor of glucose by autophagy) (Suppressor of glucose, autophagy-associated protein 1) [Cleaved into: N-terminal form; C-terminal 80 kDa form (80-kDa SOGA fragment)]
Gene: MTCL2

Interactor 2: AAPK1 (Q13131)
5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)
Gene: PRKAA1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	37340443
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1661 Hs			1 559
+	Hs
		301300 MTCL2_HUMAN (1-1661): 5.75e-170: 560: 100.00		MARK2_HUMAN (10-545): 5.04e-150: 451: 29.64
+	Hs
		301264 MTCL2_HUMAN (1-1661): 5.75e-170: 560: 100.00		MARK3_HUMAN (3-543): 7.31e-144: 434: 28.21
+	Hs
		301316 MTCL2_HUMAN (1-1661): 5.75e-170: 560: 100.00		MARK4_HUMAN (18-543): 9.01e-140: 424: 28.76
+	Rn
		100237 F7FF45_RAT (62-1441): 1.09e-39: 164: 9.57		AAPK1_RAT (1-559): 0: 593: 99.11
+	Rn
		871291 MYH9_RAT (865-1451): 8.99e-16: 85.9: 10.68		AAPK1_RAT (1-559): 0: 593: 99.11
+	Rn
		102485 G3V6P7_RAT (865-1291): 3.45e-15: 83.9: 11.16		AAPK1_RAT (1-559): 0: 593: 99.11
+	Rn
		871335 MYH10_RAT (855-1416): 5.7e-15: 83.2: 10.85		AAPK1_RAT (1-559): 0: 593: 99.11
+	Hs
		1183156 MTCL1_HUMAN (1-1119): 7.77e-57: 220: 33.25		MARK2_HUMAN (10-545): 5.04e-150: 451: 29.64
+	Hs
		647995 MTCL1_HUMAN (1-1119): 7.77e-57: 220: 33.25		MARK3_HUMAN (3-543): 7.31e-144: 434: 28.21
+	Hs
		1296792 MTCL1_HUMAN (1-1119): 7.77e-57: 220: 33.25		MARK4_HUMAN (18-543): 9.01e-140: 424: 28.76
+	Hs
		724967 MYH9_HUMAN (724-1296): 2.97e-18: 93.9: 9.74		MARK4_HUMAN (18-543): 9.01e-140: 424: 28.76
+	Hs
		725223 MYH10_HUMAN (858-1416): 2.04e-15: 84.7: 10.38		MARK4_HUMAN (18-543): 9.01e-140: 424: 28.76
+	Hs
		725010 MYH9_HUMAN (724-1296): 2.97e-18: 93.9: 9.74		SIK2_HUMAN (10-340): 1.75e-85: 286: 42.69
+	Hs
		725242 MYH10_HUMAN (858-1416): 2.04e-15: 84.7: 10.38		SIK2_HUMAN (10-340): 1.75e-85: 286: 42.69
+	Hs
		728513 MYH11_HUMAN (895-1446): 5.19e-15: 83.5: 9.48		SIK2_HUMAN (10-340): 1.75e-85: 286: 42.69