HitPredict

Interactor 1: MTCL2 (O94964)
Microtubule cross-linking factor 2 (SOGA family member 1) (Suppressor of glucose by autophagy) (Suppressor of glucose, autophagy-associated protein 1) [Cleaved into: N-terminal form; C-terminal 80 kDa form (80-kDa SOGA fragment)]
Gene: MTCL2

Interactor 2: MARK2 (Q7KZI7)
Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)
Gene: MARK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	26496610, 32707033
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1661 Hs			1 788
+	Hs
		301264 MTCL2_HUMAN (1-1661): 5.75e-170: 560: 100.00		MARK3_HUMAN (3-788): 0: 656: 60.40
+	Hs
		301316 MTCL2_HUMAN (1-1661): 5.75e-170: 560: 100.00		MARK4_HUMAN (3-788): 0: 572: 48.20
+	Hs
		1183156 MTCL1_HUMAN (1-1119): 7.77e-57: 220: 33.25		MARK2_HUMAN (1-788): 0: 790: 100.00
+	Hs
		301284 MTCL2_HUMAN (1-1661): 5.75e-170: 560: 100.00		AAPK1_HUMAN (31-560): 4.31e-139: 424: 30.37
+	Hs
		647995 MTCL1_HUMAN (1-1119): 7.77e-57: 220: 33.25		MARK3_HUMAN (3-788): 0: 656: 60.40
+	Hs
		1296792 MTCL1_HUMAN (1-1119): 7.77e-57: 220: 33.25		MARK4_HUMAN (3-788): 0: 572: 48.20
+	Hs
		724967 MYH9_HUMAN (724-1296): 2.97e-18: 93.9: 9.74		MARK4_HUMAN (3-788): 0: 572: 48.20
+	Hs
		725223 MYH10_HUMAN (858-1416): 2.04e-15: 84.7: 10.38		MARK4_HUMAN (3-788): 0: 572: 48.20
+	Rn
		100237 F7FF45_RAT (62-1441): 1.09e-39: 164: 9.57		AAPK1_RAT (31-560): 2.85e-141: 429: 30.00
+	Hs
		1344754 MYH2_HUMAN (738-1385): 1.68e-18: 94.7: 8.01		SNRK_HUMAN (48-787): 1.06e-145: 448: 23.85
+	Hs
		725010 MYH9_HUMAN (724-1296): 2.97e-18: 93.9: 9.74		SIK2_HUMAN (34-733): 3.78e-144: 448: 31.08
+	Hs
		522572 MYH1_HUMAN (738-1285): 9.94e-17: 88.9: 7.39		SNRK_HUMAN (48-787): 1.06e-145: 448: 23.85
+	Hs
		725242 MYH10_HUMAN (858-1416): 2.04e-15: 84.7: 10.38		SIK2_HUMAN (34-733): 3.78e-144: 448: 31.08
+	Hs
		728513 MYH11_HUMAN (895-1446): 5.19e-15: 83.5: 9.48		SIK2_HUMAN (34-733): 3.78e-144: 448: 31.08
+	Rn
		871291 MYH9_RAT (865-1451): 8.99e-16: 85.9: 10.68		AAPK1_RAT (31-560): 2.85e-141: 429: 30.00
+	Rn
		102485 G3V6P7_RAT (865-1291): 3.45e-15: 83.9: 11.16		AAPK1_RAT (31-560): 2.85e-141: 429: 30.00
+	Rn
		871335 MYH10_RAT (855-1416): 5.7e-15: 83.2: 10.85		AAPK1_RAT (31-560): 2.85e-141: 429: 30.00