HitPredict

Interactor 1: UBP19 (O94966)
Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19) (Zinc finger MYND domain-containing protein 9)
Gene: USP19

Interactor 2: BIRC3 (Q13489)
Baculoviral IAP repeat-containing protein 3 (EC 2.3.2.27) (Apoptosis inhibitor 2) (API2) (Cellular inhibitor of apoptosis 2) (C-IAP2) (IAP homolog C) (Inhibitor of apoptosis protein 1) (hIAP-1) (hIAP1) (RING finger protein 49) (RING-type E3 ubiquitin transferase BIRC3) (TNFR2-TRAF-signaling complex protein 1)
Gene: BIRC3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	30948266, 21849505
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0046872 - metal ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1318 Hs			1 604
+	Hs
		301386 UBP19_HUMAN (1-1318): 0: 1245: 100.00		BIRC2_HUMAN (2-604): 0: 643: 72.31
+	Hs
		301374 UBP19_HUMAN (1-1318): 0: 1245: 100.00		XIAP_HUMAN (168-604): 1.28e-83: 272: 24.21
+	Hs
		177638 UBP19_HUMAN (1-1318): 0: 1245: 100.00		BIRC5_HUMAN (258-332): 1.39e-25: 104: 35.00
+	Hs
		1036241 UBP15_HUMAN (485-1219): 1.01e-155: 496: 33.42		BIRC3_HUMAN (1-604): 0: 676: 100.00
+	Hs
		1036377 UBP15_HUMAN (485-1219): 1.01e-155: 496: 33.42		BIRC2_HUMAN (2-604): 0: 643: 72.31
+	Hs
		1035953 UBP7_HUMAN (341-968): 5.24e-54: 208: 9.64		BIRC3_HUMAN (1-604): 0: 676: 100.00
+	Hs
		1036312 UBP7_HUMAN (341-968): 5.24e-54: 208: 9.64		BIRC2_HUMAN (2-604): 0: 643: 72.31
+	Hs
		1036163 UBP35_HUMAN (1046-1284): 2.03e-43: 174: 26.42		BIRC3_HUMAN (1-604): 0: 676: 100.00
+	Hs
		849996 UBP11_HUMAN (459-1228): 1.44e-151: 484: 30.84		XIAP_HUMAN (168-604): 1.28e-83: 272: 24.21
+	Mm
		1141990 UBP15_MOUSE (485-1219): 1.25e-154: 493: 33.42		XIAP_MOUSE (147-604): 9.05e-80: 262: 24.00
+	Hs
		957751 UBP7_HUMAN (341-968): 5.24e-54: 208: 9.64		XIAP_HUMAN (168-604): 1.28e-83: 272: 24.21
+	Hs
		1264871 UBP7_HUMAN (341-968): 5.24e-54: 208: 9.64		RFFL_HUMAN (254-604): 6.11e-54: 189: 15.88
+	Hs
		777082 UBP8_HUMAN (781-1222): 3.94e-67: 250: 19.39		BIRC6_HUMAN (7-136): 3.42e-35: 144: 20.29
+	Hs
		271165 UBP2_HUMAN (796-1219): 6.05e-73: 257: 20.54		BIRC7_HUMAN (13-165): 1.87e-34: 134: 21.80
+	Hs
		1174178 UBP43_HUMAN (1019-1270): 6.95e-51: 198: 28.00		RFFL_HUMAN (254-604): 6.11e-54: 189: 15.88
+	Hs
		271156 UBP2_HUMAN (796-1219): 6.05e-73: 257: 20.54		MYLIP_HUMAN (479-603): 3.16e-23: 104: 25.60
+	Hs
		177733 UBP22_HUMAN (458-838): 9.18e-65: 231: 19.02		BIRC5_HUMAN (258-332): 1.39e-25: 104: 35.00
+	Hs
		177729 UBP35_HUMAN (1046-1284): 2.03e-43: 174: 26.42		BIRC5_HUMAN (258-332): 1.39e-25: 104: 35.00