HitPredict

Interactor 1: UBP19 (O94966)
Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19) (Zinc finger MYND domain-containing protein 9)
Gene: USP19

Interactor 2: FKBP8 (Q14318)
Peptidyl-prolyl cis-trans isomerase FKBP8 (PPIase FKBP8) (EC 5.2.1.8) (38 kDa FK506-binding protein) (38 kDa FKBP) (FKBP-38) (hFKBP38) (FK506-binding protein 8) (FKBP-8) (FKBPR38) (Rotamase)
Gene: FKBP8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	32877691, 19615732
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005829 - cytosol GO:0046872 - metal ion binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1318 Hs			1 412
+	Hs
		259907 UBP19_HUMAN (1-1318): 0: 1245: 100.00		FKBP6_HUMAN (81-380): 6.91e-56: 188: 23.73
+	Hs
		118659 UBP19_HUMAN (1-1318): 0: 1245: 100.00		AIP_HUMAN (97-369): 4.45e-54: 184: 18.94
+	Hs
		301455 UBP19_HUMAN (1-1318): 0: 1245: 100.00		FKBPL_HUMAN (8-369): 7.94e-52: 178: 22.43
+	Hs
		301376 UBP19_HUMAN (1-1318): 0: 1245: 100.00		FKBP4_HUMAN (72-404): 6.45e-24: 105: 18.18
+	Hs
		301362 UBP19_HUMAN (1-1318): 0: 1245: 100.00		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00
+	Hs
		1035070 UBP15_HUMAN (485-1219): 1.01e-155: 496: 33.42		FKBP5_HUMAN (72-203): 1.44e-18: 89.2: 27.21
+	Hs
		684939 UBP7_HUMAN (341-968): 5.24e-54: 208: 9.64		STIP1_HUMAN (218-357): 3.76e-20: 94.2: 20.00