Interactor 1: UBP19 (O94966)
Ubiquitin carboxyl-terminal hydrolase 19 (EC 3.4.19.12) (Deubiquitinating enzyme 19) (Ubiquitin thioesterase 19) (Ubiquitin-specific-processing protease 19) (Zinc finger MYND domain-containing protein 9)
Gene: USP19

Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 19615732
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains UCH~UCH, UCH~USP7_C2
Common GO terms GO:0004843 - cysteine-type deubiquitinase activity
GO:0005829 - cytosol
GO:0016579 - protein deubiquitination
GO:0031647 - regulation of protein stability
GO:0050821 - protein stabilization
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1318
Hs

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Last updated: 15 Jul 2024