HitPredict

Interactor 1: WDR47 (O94967)
WD repeat-containing protein 47 (Neuronal enriched MAP-interacting protein) (Nemitin)
Gene: WDR47

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35063084
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005737 - cytoplasm GO:0005874 - microtubule GO:0030425 - dendrite GO:0030426 - growth cone and 1 others more... GO:0043025 - neuronal cell body
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 919 Hs			1 758
+	Hs
		496777 GBB2_HUMAN (563-916): 3.54e-78: 259: 20.17		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496503 LIS1_HUMAN (838-919): 4.39e-20: 96: 28.05		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		653951 WDR5_HUMAN (471-827): 1.65e-75: 252: 14.88		MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56
+	Hs
		497176 A16L1_HUMAN (835-918): 6.18e-13: 74.8: 21.43		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		152622 WDR5_HUMAN (471-827): 1.65e-75: 252: 14.88		KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55
+	Hs
		152663 WDR5B_HUMAN (476-827): 6.86e-75: 250: 15.56		KMT2D_HUMAN (226-636): 8.62e-26: 116: 19.55
+	Hs
		921574 GBB2_HUMAN (563-916): 3.54e-78: 259: 20.17		SPEG_HUMAN (183-564): 6e-23: 107: 16.71
+	Mm
		497983 GNB5_MOUSE (645-874): 2.82e-14: 77.8: 27.31		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Mm
		903669 WDR5_MOUSE (471-827): 1.65e-75: 252: 14.88		KMT2C_MOUSE (228-587): 6.06e-09: 61.9: 16.84
+	Hs
		903374 WDR5_HUMAN (471-827): 1.65e-75: 252: 14.88		KMT2C_HUMAN (83-649): 6.28e-09: 61.8: 12.91
+	Hs
		1056932 SNR40_HUMAN (555-872): 4.15e-50: 182: 16.26		MDC1_HUMAN (2-755): 3.72e-28: 124: 8.57
+	Hs
		653993 A16L1_HUMAN (835-918): 6.18e-13: 74.8: 21.43		MAP4_HUMAN (3-742): 6.73e-32: 135: 20.56
+	Mm
		649213 A16L1_MOUSE (836-918): 2.95e-12: 72.4: 22.89		MAP4_MOUSE (10-742): 3.04e-29: 127: 18.63
+	Hs
		1078285 A16L1_HUMAN (835-918): 6.18e-13: 74.8: 21.43		SPEG_HUMAN (183-564): 6e-23: 107: 16.71
+	Dm
		1370295 POC1_DROME (530-703): 4.4e-19: 92.4: 17.82		Q9VLS7_DROME (62-753): 1.93e-12: 73.2: 9.96
+	Mm
		1207691 A16L1_MOUSE (836-918): 2.95e-12: 72.4: 22.89		TARA_MOUSE (3-751): 2.63e-09: 63.2: 8.51