HitPredict

Interactor 1: TRI37 (O94972)
E3 ubiquitin-protein ligase TRIM37 (EC 2.3.2.27) (Mulibrey nanism protein) (RING-type E3 ubiquitin transferase TRIM37) (Tripartite motif-containing protein 37)
Gene: TRIM37

Interactor 2: K2C1 (P04264)
Keratin, type II cytoskeletal 1 (67 kDa cytokeratin) (Cytokeratin-1) (CK-1) (Hair alpha protein) (Keratin-1) (K1) (Type-II keratin Kb1)
Gene: KRT1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33194618
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 964 Hs			1 644
+	Hs
		301540 TRI37_HUMAN (1-964): 0: 1280: 100.00		K2C8_HUMAN (152-543): 4.05e-144: 429: 59.44
+	Hs
		301560 TRI37_HUMAN (1-964): 0: 1280: 100.00		K2C7_HUMAN (138-505): 3.95e-137: 410: 60.33
+	Hs
		301586 TRI37_HUMAN (1-964): 0: 1280: 100.00		K2C5_HUMAN (1-496): 2.32e-82: 272: 64.32
+	Hs
		301525 TRI37_HUMAN (1-964): 0: 1280: 100.00		K2C6B_HUMAN (2-512): 5.16e-79: 263: 62.82
+	Hs
		301515 TRI37_HUMAN (1-964): 0: 1280: 100.00		K2C6A_HUMAN (2-512): 2.12e-75: 253: 62.43
+	Hs
		301896 TRI37_HUMAN (1-964): 0: 1280: 100.00		K2C74_HUMAN (1-559): 3.34e-71: 241: 52.59
+	Hs
		318774 TRI27_HUMAN (1-373): 2.44e-71: 247: 16.00		K2C75_HUMAN (1-579): 4.51e-88: 286: 53.89
+	Hs
		380552 TRI27_HUMAN (1-373): 2.44e-71: 247: 16.00		K2C1_HUMAN (1-511): 2.63e-77: 260: 100.00
+	Hs
		531606 TRI58_HUMAN (1-372): 1.91e-67: 235: 16.15		K2C5_HUMAN (1-496): 2.32e-82: 272: 64.32
+	Hs
		536787 TRI27_HUMAN (1-373): 2.44e-71: 247: 16.00		K22O_HUMAN (1-508): 2.87e-69: 239: 60.00
+	Hs
		531626 TRI31_HUMAN (1-287): 1.23e-58: 209: 17.11		K2C5_HUMAN (1-496): 2.32e-82: 272: 64.32
+	Hs
		380469 TRI26_HUMAN (1-299): 2e-58: 211: 18.10		K2C6B_HUMAN (2-512): 5.16e-79: 263: 62.82
+	Hs
		821686 TRIM7_HUMAN (10-361): 1.45e-58: 211: 15.83		K2C6C_HUMAN (2-512): 2.69e-78: 261: 62.62
+	Hs
		380683 TRIM7_HUMAN (10-361): 1.45e-58: 211: 15.83		K2C1_HUMAN (1-511): 2.63e-77: 260: 100.00
+	Hs
		380682 TRI31_HUMAN (1-287): 1.23e-58: 209: 17.11		K2C1_HUMAN (1-511): 2.63e-77: 260: 100.00
+	Hs
		380492 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		K2C6B_HUMAN (2-512): 5.16e-79: 263: 62.82
+	Hs
		517736 TRI27_HUMAN (1-373): 2.44e-71: 247: 16.00		K2C3_HUMAN (152-497): 1.64e-62: 220: 74.71
+	Hs
		380639 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		K2C1_HUMAN (1-511): 2.63e-77: 260: 100.00
+	Hs
		359506 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		K2C6A_HUMAN (2-512): 2.12e-75: 253: 62.43
+	Hs
		1062065 TRI31_HUMAN (1-287): 1.23e-58: 209: 17.11		K2C72_HUMAN (90-496): 1.88e-73: 247: 61.92