HitPredict

Interactor 1: TRI37 (O94972)
E3 ubiquitin-protein ligase TRIM37 (EC 2.3.2.27) (Mulibrey nanism protein) (RING-type E3 ubiquitin transferase TRIM37) (Tripartite motif-containing protein 37)
Gene: TRIM37

Interactor 2: HSP7C (P11142)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8) (Heat shock protein family A member 8) (Lipopolysaccharide-associated protein 1) (LAP-1) (LPS-associated protein 1)
Gene: HSPA8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32908313, 33194618
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 964 Hs			1 646
+	Hs
		504715 TRIM6_HUMAN (1-360): 9.92e-70: 242: 17.10		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		563999 RO52_HUMAN (1-393): 1.7e-71: 246: 16.54		HSP76_HUMAN (6-646): 0: 955: 77.54
+	Hs
		504713 TRIM9_HUMAN (7-367): 6.34e-58: 214: 17.71		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		503987 TRI26_HUMAN (1-299): 2e-58: 211: 18.10		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		504714 TRIM7_HUMAN (10-361): 1.45e-58: 211: 15.83		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		504712 TRI31_HUMAN (1-287): 1.23e-58: 209: 17.11		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		504282 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		564176 TRI31_HUMAN (1-287): 1.23e-58: 209: 17.11		HSP76_HUMAN (6-646): 0: 955: 77.54
+	Hs
		564101 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		HSP76_HUMAN (6-646): 0: 955: 77.54
+	Hs
		1120600 TRI17_HUMAN (1-343): 4.52e-57: 206: 18.21		Q53FC7_HUMAN (6-646): 0: 951: 77.07
+	Hs
		871632 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		HSP72_HUMAN (2-646): 0: 940: 85.47
+	Hs
		135007 TRI38_HUMAN (3-258): 7.74e-37: 147: 18.18		HSP7C_HUMAN (1-646): 0: 967: 100.00
+	Hs
		135010 TRI38_HUMAN (3-258): 7.74e-37: 147: 18.18		HS71L_HUMAN (2-646): 0: 966: 82.48
+	Hs
		135015 TRI38_HUMAN (3-258): 7.74e-37: 147: 18.18		HSP72_HUMAN (2-646): 0: 940: 85.47