HitPredict

Interactor 1: TRI37 (O94972)
E3 ubiquitin-protein ligase TRIM37 (EC 2.3.2.27) (Mulibrey nanism protein) (RING-type E3 ubiquitin transferase TRIM37) (Tripartite motif-containing protein 37)
Gene: TRIM37

Interactor 2: KPYM (P14618)
Pyruvate kinase PKM (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Threonine-protein kinase PKM2) (EC 2.7.11.1) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (Tyrosine-protein kinase PKM2) (EC 2.7.10.2) (p58)
Gene: PKM

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33194618
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0042803 - protein homodimerization activity
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 964 Hs			1 531
+	Hs
		537966 TRI58_HUMAN (1-372): 1.91e-67: 235: 16.15		KPYM_HUMAN (1-531): 0: 801: 100.00
+	Hs
		538063 TRI35_HUMAN (5-371): 7.76e-65: 228: 16.71		KPYM_HUMAN (1-531): 0: 801: 100.00
+	Hs
		538019 TRI31_HUMAN (1-287): 1.23e-58: 209: 17.11		KPYM_HUMAN (1-531): 0: 801: 100.00
+	Hs
		537940 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		KPYM_HUMAN (1-531): 0: 801: 100.00