HitPredict

Interactor 1: TRI37 (O94972)
E3 ubiquitin-protein ligase TRIM37 (EC 2.3.2.27) (Mulibrey nanism protein) (RING-type E3 ubiquitin transferase TRIM37) (Tripartite motif-containing protein 37)
Gene: TRIM37

Interactor 2: ARP3 (P61158)
Actin-related protein 3 (Actin-like protein 3)
Gene: ACTR3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33194618
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 964 Hs			1 418
+	Hs
		301705 TRI37_HUMAN (1-964): 0: 1280: 100.00		ACTB_HUMAN (1-414): 0: 539: 35.66
+	Hs
		301752 TRI37_HUMAN (1-964): 0: 1280: 100.00		ACTS_HUMAN (3-414): 0: 528: 35.59
+	Hs
		301750 TRI37_HUMAN (1-964): 0: 1280: 100.00		ACTC_HUMAN (3-414): 0: 527: 35.59
+	Hs
		896767 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		ARP3_HUMAN (1-418): 0: 588: 100.00
+	Hs
		584915 RO52_HUMAN (1-393): 1.7e-71: 246: 16.54		ACTB_HUMAN (1-414): 0: 539: 35.66
+	Hs
		891904 TRI58_HUMAN (1-372): 1.91e-67: 235: 16.15		ACTB_HUMAN (1-414): 0: 539: 35.66
+	Hs
		584922 RO52_HUMAN (1-393): 1.7e-71: 246: 16.54		ACTA_HUMAN (3-414): 0: 526: 35.59
+	Hs
		933049 TRIM6_HUMAN (1-360): 9.92e-70: 242: 17.10		ACTS_HUMAN (3-414): 0: 528: 35.59
+	Hs
		930096 TRIM6_HUMAN (1-360): 9.92e-70: 242: 17.10		ACTH_HUMAN (3-414): 0: 524: 35.59
+	Hs
		892017 TRIM9_HUMAN (7-367): 6.34e-58: 214: 17.71		ACTB_HUMAN (1-414): 0: 539: 35.66
+	Hs
		891732 TRI26_HUMAN (1-299): 2e-58: 211: 18.10		ACTB_HUMAN (1-414): 0: 539: 35.66
+	Hs
		892015 TRI31_HUMAN (1-287): 1.23e-58: 209: 17.11		ACTB_HUMAN (1-414): 0: 539: 35.66
+	Hs
		891854 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		ACTB_HUMAN (1-414): 0: 539: 35.66
+	Hs
		929906 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		ACTG_HUMAN (1-414): 0: 538: 35.42
+	Hs
		932366 TRIM9_HUMAN (7-367): 6.34e-58: 214: 17.71		ACTC_HUMAN (3-414): 0: 527: 35.59
+	Hs
		915499 TRIM9_HUMAN (7-367): 6.34e-58: 214: 17.71		ACTA_HUMAN (3-414): 0: 526: 35.59
+	Hs
		933048 TRI31_HUMAN (1-287): 1.23e-58: 209: 17.11		ACTS_HUMAN (3-414): 0: 528: 35.59
+	Hs
		932220 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		ACTC_HUMAN (3-414): 0: 527: 35.59
+	Hs
		915417 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		ACTA_HUMAN (3-414): 0: 526: 35.59
+	Hs
		930086 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		ACTH_HUMAN (3-414): 0: 524: 35.59