HitPredict

Interactor 1: TRI37 (O94972)
E3 ubiquitin-protein ligase TRIM37 (EC 2.3.2.27) (Mulibrey nanism protein) (RING-type E3 ubiquitin transferase TRIM37) (Tripartite motif-containing protein 37)
Gene: TRIM37

Interactor 2: UBE2H (P62256)
Ubiquitin-conjugating enzyme E2 H (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme H) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme H) (UbcH2) (Ubiquitin carrier protein H) (Ubiquitin-conjugating enzyme E2-20K) (Ubiquitin-protein ligase H)
Gene: UBE2H

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	19549727
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 964 Hs			1 183
+	Hs
		301733 TRI37_HUMAN (1-964): 0: 1280: 100.00		UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73
+	Hs
		301690 TRI37_HUMAN (1-964): 0: 1280: 100.00		UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43
+	Hs
		301711 TRI37_HUMAN (1-964): 0: 1280: 100.00		UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05
+	Hs
		301956 TRI37_HUMAN (1-964): 0: 1280: 100.00		UB2E3_HUMAN (5-150): 1.84e-65: 201: 28.00
+	Hs
		301973 TRI37_HUMAN (1-964): 0: 1280: 100.00		UB2E2_HUMAN (5-150): 1.61e-65: 201: 27.33
+	Hs
		301691 TRI37_HUMAN (1-964): 0: 1280: 100.00		UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33
+	Hs
		1285831 TRI43_HUMAN (1-372): 1.51e-75: 257: 17.36		UB2D4_HUMAN (7-150): 2.75e-73: 218: 31.08
+	Hs
		919816 TRI43_HUMAN (1-372): 1.51e-75: 257: 17.36		UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73
+	Hs
		849399 TRI43_HUMAN (1-372): 1.51e-75: 257: 17.36		UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43
+	Hs
		919822 TRI11_HUMAN (1-360): 2.21e-74: 254: 16.04		UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73
+	Hs
		849406 TRI11_HUMAN (1-360): 2.21e-74: 254: 16.04		UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43
+	Hs
		895870 TRI43_HUMAN (1-372): 1.51e-75: 257: 17.36		UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05
+	Hs
		895876 TRI11_HUMAN (1-360): 2.21e-74: 254: 16.04		UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05
+	Hs
		536779 TRI27_HUMAN (1-373): 2.44e-71: 247: 16.00		UB2D2_HUMAN (7-150): 8.88e-73: 217: 29.73
+	Hs
		536760 TRI27_HUMAN (1-373): 2.44e-71: 247: 16.00		UB2D1_HUMAN (7-150): 2.2e-72: 216: 32.43
+	Hs
		536772 TRI27_HUMAN (1-373): 2.44e-71: 247: 16.00		UB2D3_HUMAN (7-150): 5.39e-71: 213: 29.05
+	Hs
		851867 TRI11_HUMAN (1-360): 2.21e-74: 254: 16.04		UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33
+	Hs
		536757 TRI27_HUMAN (1-373): 2.44e-71: 247: 16.00		UBE2A_HUMAN (4-150): 8.87e-65: 197: 30.46
+	Hs
		536763 TRI27_HUMAN (1-373): 2.44e-71: 247: 16.00		UB2E1_HUMAN (5-150): 3.02e-64: 197: 27.33
+	Hs
		536776 TRI27_HUMAN (1-373): 2.44e-71: 247: 16.00		UBE2H_HUMAN (1-183): 8.84e-64: 196: 100.00