HitPredict

Interactor 1: TRI37 (O94972)
E3 ubiquitin-protein ligase TRIM37 (EC 2.3.2.27) (Mulibrey nanism protein) (RING-type E3 ubiquitin transferase TRIM37) (Tripartite motif-containing protein 37)
Gene: TRIM37

Interactor 2: LRP1 (Q07954)
Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]
Gene: LRP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	32908313
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 964 Hs			1 4544
+	Hs
		992679 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		LRP1_HUMAN (24-4544): 0: 3520: 100.00
+	Hs
		301776 TRI37_HUMAN (1-964): 0: 1280: 100.00		NOTC2_HUMAN (2441-2811): 3.71e-13: 79.1: 10.70
+	Hs
		301513 TRI37_HUMAN (1-964): 0: 1280: 100.00		LDLR_HUMAN (4062-4338): 4.81e-10: 68.3: 11.95
+	Hs
		1171059 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		SORL_HUMAN (4091-4375): 6.29e-11: 71.4: 12.95
+	Hs
		270305 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		LRP6_HUMAN (26-203): 6.89e-11: 71.4: 20.44
+	Hs
		351080 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		LDLR_HUMAN (4062-4338): 4.81e-10: 68.3: 11.95
+	Hs
		1048442 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		LRP8_HUMAN (4104-4404): 8.77e-10: 67.6: 11.54