HitPredict

Interactor 1: TRI37 (O94972)
E3 ubiquitin-protein ligase TRIM37 (EC 2.3.2.27) (Mulibrey nanism protein) (RING-type E3 ubiquitin transferase TRIM37) (Tripartite motif-containing protein 37)
Gene: TRIM37

Interactor 2: HIF1A (Q16665)
Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8)
Gene: HIF1A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34611473
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 964 Hs			1 826
+	Hs
		302072 TRI37_HUMAN (1-964): 0: 1280: 100.00		X5DP31_HUMAN (2-524): 3.31e-118: 374: 20.31
+	Hs
		302010 TRI37_HUMAN (1-964): 0: 1280: 100.00		ARNT2_HUMAN (2-573): 2.8e-114: 365: 18.75
+	Hs
		584973 RO52_HUMAN (1-393): 1.7e-71: 246: 16.54		HIF1A_HUMAN (1-826): 0: 741: 100.00
+	Hs
		537157 TRI27_HUMAN (1-373): 2.44e-71: 247: 16.00		X5DP31_HUMAN (2-524): 3.31e-118: 374: 20.31
+	Hs
		537076 TRI27_HUMAN (1-373): 2.44e-71: 247: 16.00		ARNT2_HUMAN (2-573): 2.8e-114: 365: 18.75
+	Hs
		585104 RO52_HUMAN (1-393): 1.7e-71: 246: 16.54		NCOA3_HUMAN (1-746): 4.42e-98: 335: 15.31