HitPredict

Interactor 1: TRI37 (O94972)
E3 ubiquitin-protein ligase TRIM37 (EC 2.3.2.27) (Mulibrey nanism protein) (RING-type E3 ubiquitin transferase TRIM37) (Tripartite motif-containing protein 37)
Gene: TRIM37

Interactor 2: FTM (Q68CZ1)
Protein fantom (Nephrocystin-8) (RPGR-interacting protein 1-like protein) (RPGRIP1-like protein)
Gene: RPGRIP1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.643

Property	Details
Experiments	26638075, 32908313, unassigned1272
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 964 Hs			1 1315
+	Hs
		301970 TRI37_HUMAN (1-964): 0: 1280: 100.00		RPGR1_HUMAN (253-1313): 0: 631: 31.62
+	Hs
		301948 TRI37_HUMAN (1-964): 0: 1280: 100.00		MY18A_HUMAN (1-545): 3.87e-28: 126: 11.03
+	Hs
		301580 TRI37_HUMAN (1-964): 0: 1280: 100.00		MYH7_HUMAN (199-778): 1.36e-22: 107: 11.21
+	Hs
		302036 TRI37_HUMAN (1-964): 0: 1280: 100.00		MYH13_HUMAN (201-793): 1.62e-20: 101: 12.50
+	Hs
		302035 TRI37_HUMAN (1-964): 0: 1280: 100.00		MYH2_HUMAN (260-783): 4.84e-17: 89.4: 10.76
+	Hs
		301650 TRI37_HUMAN (1-964): 0: 1280: 100.00		MYH9_HUMAN (125-627): 6.2e-16: 85.8: 15.48
+	Hs
		302067 TRI37_HUMAN (1-964): 0: 1280: 100.00		MYH4_HUMAN (260-783): 2.35e-15: 84.1: 11.32
+	Hs
		301596 TRI37_HUMAN (1-964): 0: 1280: 100.00		DESP_HUMAN (57-798): 1.13e-13: 78.7: 10.51
+	Hs
		536879 TRI27_HUMAN (1-373): 2.44e-71: 247: 16.00		FTM_HUMAN (1-1315): 0: 899: 100.00
+	Mm
		1143601 TRI27_MOUSE (1-373): 8.96e-72: 248: 16.00		FTM_MOUSE (1-1315): 0: 775: 81.99
+	Hs
		149258 TRIM4_HUMAN (7-372): 1.03e-66: 234: 14.04		CTRO_HUMAN (1-542): 6.86e-25: 115: 9.73
+	Hs
		522639 TRIM6_HUMAN (1-360): 9.92e-70: 242: 17.10		MYH7_HUMAN (199-778): 1.36e-22: 107: 11.21
+	Hs
		1290898 TRI11_HUMAN (1-360): 2.21e-74: 254: 16.04		DAPLE_HUMAN (64-568): 9.7e-13: 75.3: 17.26
+	Hs
		528393 TRIM6_HUMAN (1-360): 9.92e-70: 242: 17.10		MYH6_HUMAN (1-465): 4.57e-16: 86.4: 11.04
+	Hs
		148970 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		CTRO_HUMAN (1-542): 6.86e-25: 115: 9.73
+	Mm
		1093546 TRI72_MOUSE (3-319): 6.9e-58: 208: 15.98		MYH9_MOUSE (1-496): 3.14e-18: 93.3: 12.25
+	Hs
		1357714 TRI35_HUMAN (5-371): 7.76e-65: 228: 16.71		MRCKB_HUMAN (120-586): 4.94e-12: 73: 14.18
+	Hs
		725005 TRI31_HUMAN (1-287): 1.23e-58: 209: 17.11		MYH9_HUMAN (125-627): 6.2e-16: 85.8: 15.48
+	Hs
		551749 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		DESP_HUMAN (57-798): 1.13e-13: 78.7: 10.51
+	Hs
		254493 TRI67_HUMAN (2-368): 1.83e-54: 205: 15.93		ROCK2_HUMAN (320-782): 9.76e-12: 72.1: 9.66