HitPredict

Interactor 1: AP2A2 (O94973)
AP-2 complex subunit alpha-2 (100 kDa coated vesicle protein C) (Adaptor protein complex AP-2 subunit alpha-2) (Adaptor-related protein complex 2 subunit alpha-2) (Alpha-adaptin C) (Alpha2-adaptin) (Clathrin assembly protein complex 2 alpha-C large chain) (Huntingtin yeast partner J) (Huntingtin-interacting protein 9) (HIP-9) (Huntingtin-interacting protein J) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit)
Gene: AP2A2

Interactor 2: RNF6 (Q9Y252)
E3 ubiquitin-protein ligase RNF6 (EC 2.3.2.27)
Gene: RNF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	27684187
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 939 Hs			1 685
+	Hs
		302201 AP2A2_HUMAN (1-939): 0: 884: 100.00		RN126_HUMAN (503-684): 8.83e-31: 124: 23.37
+	Hs
		321676 AP2A1_HUMAN (1-939): 0: 832: 78.47		RNF11_HUMAN (525-676): 1.63e-30: 119: 28.76
+	Hs
		212647 AP1G1_HUMAN (1-811): 0: 616: 25.12		RN149_HUMAN (576-679): 5.5e-30: 124: 27.62
+	Hs
		926060 AP2B1_HUMAN (36-933): 0: 607: 16.62		RNF11_HUMAN (525-676): 1.63e-30: 119: 28.76
+	Hs
		207529 AP1G2_HUMAN (13-816): 0: 554: 25.83		RNF13_HUMAN (608-679): 2e-26: 113: 35.62
+	Hs
		150136 AP3D1_HUMAN (11-478): 3.33e-33: 140: 23.51		RNF13_HUMAN (608-679): 2e-26: 113: 35.62