HitPredict

Interactor 1: SC31A (O94979)
Protein transport protein Sec31A (ABP125) (ABP130) (SEC31-like protein 1) (SEC31-related protein A) (Web1-like protein)
Gene: SEC31A

Interactor 2: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1220 Hs			1 839
+	Hs
		302238 SC31A_HUMAN (1-1220): 0: 830: 100.00		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		302247 SC31A_HUMAN (1-1220): 0: 830: 100.00		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		302255 SC31A_HUMAN (1-1220): 0: 830: 100.00		FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57
+	Hs
		302241 SC31A_HUMAN (1-1220): 0: 830: 100.00		RET_HUMAN (282-837): 1.5e-108: 360: 25.76
+	Hs
		302242 SC31A_HUMAN (1-1220): 0: 830: 100.00		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Hs
		302332 SC31A_HUMAN (1-1220): 0: 830: 100.00		ALK_HUMAN (513-816): 2.78e-59: 222: 39.03
+	Rn
		102464 G3V699_RAT (1-1220): 0: 769: 87.38		INSR_RAT (513-824): 3.31e-62: 230: 38.80
+	Hs
		169154 SC31A_HUMAN (1-1220): 0: 830: 100.00		MUSK_HUMAN (209-391): 1.75e-22: 105: 24.60
+	Hs
		725460 COPB2_HUMAN (1-243): 1.76e-41: 167: 12.30		NTRK3_HUMAN (1-839): 0: 671: 100.00
+	Hs
		384726 RBBP4_HUMAN (9-349): 7.97e-83: 279: 17.49		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		385480 TBL1R_HUMAN (17-335): 7.88e-65: 231: 15.51		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		384596 WDR5_HUMAN (206-522): 2.88e-60: 212: 14.95		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		384386 COPB2_HUMAN (1-243): 1.76e-41: 167: 12.30		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		507887 COPB2_HUMAN (1-243): 1.76e-41: 167: 12.30		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		384438 LIS1_HUMAN (331-619): 6.2e-16: 83.4: 7.74		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		609202 LIS1_HUMAN (331-619): 6.2e-16: 83.4: 7.74		FGFR3_HUMAN (140-838): 3.83e-170: 514: 23.73
+	Hs
		411323 COPB2_HUMAN (1-243): 1.76e-41: 167: 12.30		INSR_HUMAN (513-824): 1.34e-64: 238: 39.43
+	Hs
		725611 COPB2_HUMAN (1-243): 1.76e-41: 167: 12.30		ALK_HUMAN (513-816): 2.78e-59: 222: 39.03
+	Hs
		169165 COPB2_HUMAN (1-243): 1.76e-41: 167: 12.30		MUSK_HUMAN (209-391): 1.75e-22: 105: 24.60