HitPredict

Interactor 1: SC31A (O94979)
Protein transport protein Sec31A (ABP125) (ABP130) (SEC31-like protein 1) (SEC31-related protein A) (Web1-like protein)
Gene: SEC31A

Interactor 2: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	21653829
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1220 Hs			1 1164
+	Hs
		148240 SC31A_HUMAN (1-1220): 0: 830: 100.00		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		149330 SC31B_HUMAN (1-1220): 0: 612: 45.00		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		148728 RBBP4_HUMAN (9-349): 7.97e-83: 279: 17.49		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		551682 RBBP4_HUMAN (9-349): 7.97e-83: 279: 17.49		DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54
+	Hs
		903399 WDR5_HUMAN (206-522): 2.88e-60: 212: 14.95		MY18A_HUMAN (461-1064): 4e-25: 115: 10.31
+	Hs
		148610 WDR5_HUMAN (206-522): 2.88e-60: 212: 14.95		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		551655 WDR5_HUMAN (206-522): 2.88e-60: 212: 14.95		DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54
+	Hs
		792983 LIS1_HUMAN (331-619): 6.2e-16: 83.4: 7.74		DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33
+	Bt
		60990 LIS1_BOVIN (331-619): 8.26e-16: 83: 7.74		A5PKJ3_BOVIN (540-1022): 3.36e-54: 209: 17.38
+	Hs
		551766 WDR5B_HUMAN (1-244): 1.46e-50: 183: 12.96		DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54
+	Hs
		903285 WDR5_HUMAN (206-522): 2.88e-60: 212: 14.95		CYTSB_HUMAN (740-1117): 1.86e-12: 74.1: 12.41
+	Hs
		903334 WDR5_HUMAN (206-522): 2.88e-60: 212: 14.95		MYH14_HUMAN (620-918): 1.78e-11: 71.1: 13.11
+	Hs
		148462 COPB2_HUMAN (1-243): 1.76e-41: 167: 12.30		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		551854 NLE1_HUMAN (243-545): 1.47e-43: 168: 10.29		DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54
+	Hs
		148871 RBBP7_HUMAN (17-155): 1.09e-16: 86: 14.19		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		551632 LIS1_HUMAN (331-619): 6.2e-16: 83.4: 7.74		DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54
+	Hs
		969591 RBBP7_HUMAN (17-155): 1.09e-16: 86: 14.19		CENPE_HUMAN (620-984): 9.03e-10: 65.5: 20.36
+	Dm
		1099162 CAF1_DROME (17-155): 5.47e-17: 87.2: 13.51		Q9VCC9_DROME (835-1160): 2.53e-09: 63.7: 9.76
+	Hs
		792973 LIS1_HUMAN (331-619): 6.2e-16: 83.4: 7.74		CENPE_HUMAN (620-984): 9.03e-10: 65.5: 20.36
+	Dm
		1249256 Q8SYL1_DROME (14-226): 7.26e-14: 77.7: 20.78		Q9VCC9_DROME (835-1160): 2.53e-09: 63.7: 9.76