HitPredict

Interactor 1: CE152 (O94986)
Centrosomal protein of 152 kDa (Cep152)
Gene: CEP152

Interactor 2: CEP63 (Q96MT8)
Centrosomal protein of 63 kDa (Cep63)
Gene: CEP63

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.689

Property	Details
Experiments	24613305, 26638075, 33961781, 26297806
Identification Methods	proximity labelling technology, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005814 - centriole GO:0005829 - cytosol GO:0007099 - centriole replication GO:0098535 - de novo centriole assembly involved in multi-ciliated epithelial cell differentiation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1710 Hs			1 703
+	Hs
		302507 CE152_HUMAN (1-1710): 1.35e-138: 473: 100.00		DEUP1_HUMAN (8-523): 1.03e-62: 221: 28.30
+	Mm
		57606 CE152_MOUSE (1-1706): 3.8e-107: 380: 60.05		DEUP1_MOUSE (8-523): 3.71e-62: 220: 27.78
+	Hs
		302485 CE152_HUMAN (1-1710): 1.35e-138: 473: 100.00		MYH10_HUMAN (145-703): 1.35e-24: 112: 10.78
+	Mm
		57604 CE152_MOUSE (1-1706): 3.8e-107: 380: 60.05		CEP63_MOUSE (1-702): 4.16e-54: 199: 80.20
+	Mm
		57607 CE152_MOUSE (1-1706): 3.8e-107: 380: 60.05		U5KUF9_MOUSE (8-457): 4.16e-45: 171: 25.27
+	Hs
		302534 CE152_HUMAN (1-1710): 1.35e-138: 473: 100.00		CROCC_HUMAN (102-701): 1.82e-12: 73.2: 9.08
+	Hs
		302594 CE152_HUMAN (1-1710): 1.35e-138: 473: 100.00		CP250_HUMAN (150-696): 7.75e-10: 64.8: 11.94
+	Hs
		1298045 CP250_HUMAN (1-935): 4.85e-30: 133: 9.24		CEP63_HUMAN (1-703): 1.84e-64: 228: 100.00
+	Hs
		725097 MYH11_HUMAN (4-923): 1.03e-43: 177: 10.61		MYH10_HUMAN (145-703): 1.35e-24: 112: 10.78
+	Hs
		148466 MYH11_HUMAN (4-923): 1.03e-43: 177: 10.61		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Dm
		1303379 MYSN_DROME (465-1530): 1.16e-38: 161: 9.37		MYSN_DROME (1-430): 3.81e-15: 82.1: 12.70
+	Rn
		361106 MYH6_RAT (648-1564): 3.16e-35: 149: 9.14		MYH6_RAT (1-521): 9.79e-18: 90.4: 11.77
+	Hs
		528432 MYH13_HUMAN (832-1562): 6.31e-26: 119: 9.17		MYH8_HUMAN (2-701): 1.11e-26: 119: 11.69
+	Hs
		724994 CP250_HUMAN (1-935): 4.85e-30: 133: 9.24		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		1113839 CP250_HUMAN (1-935): 4.85e-30: 133: 9.24		GRDN_HUMAN (150-697): 6.94e-17: 87.5: 12.91
+	Hs
		724687 MYH10_HUMAN (7-702): 1.82e-24: 114: 8.71		MYH9_HUMAN (1-520): 3.09e-20: 98.3: 12.02
+	Hs
		502933 MYH3_HUMAN (832-1534): 1.49e-24: 114: 8.77		MYH4_HUMAN (2-477): 5.27e-17: 87.9: 10.65
+	Hs
		148461 MYH10_HUMAN (7-702): 1.82e-24: 114: 8.71		CTRO_HUMAN (22-572): 2.81e-16: 85.5: 13.29
+	Hs
		502901 MYH3_HUMAN (832-1534): 1.49e-24: 114: 8.77		MYH6_HUMAN (300-700): 3.66e-13: 75.5: 11.47
+	Mm
		93570 MYH9_MOUSE (840-1570): 5e-28: 126: 9.40		DESP_MOUSE (59-550): 4.18e-09: 62.5: 18.91