HitPredict

Interactor 1: A0A0H3NK16 (A0A0H3NK16)
Envelope stress response regulator transcription factor CpxR (Two-component response regulatory protein)
Gene: cpxR

Interactor 2: A0A0H3NUZ2 (A0A0H3NUZ2)
histidine kinase (EC 2.7.13.3)
Gene: cpxA

Species: Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.578

Property	Details
Experiments	21472855
Identification Methods	pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	HATPase_c~Response_reg, HisKA~Response_reg
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 232 Se			1 457
+	Ec
		468133 CPXR_ECOLI (1-232): 1.97e-69: 214: 97.41		CPXA_ECOLI (1-457): 7.24e-153: 443: 96.94
+	Ss
		937545 P72948_SYNY3 (1-229): 9.74e-74: 225: 37.77		Q55475_SYNY3 (145-453): 1.27e-65: 218: 25.47
+	Mx
		1091479 Q1DCL7_MYXXD (4-229): 5.41e-71: 218: 38.16		Q1D333_MYXXD (227-457): 2.68e-61: 208: 29.71
+	Ec
		676783 BAER_ECOLI (2-232): 7.92e-70: 215: 36.21		BAES_ECOLI (147-456): 7.82e-60: 204: 25.08
+	Ec
		940183 HPRR_ECOLI (2-230): 1.2e-66: 206: 36.09		HPRS_ECOLI (165-452): 9.79e-63: 211: 22.79
+	Mx
		1091444 Q1D1K9_MYXXD (3-231): 3.51e-67: 208: 42.61		Q1D333_MYXXD (227-457): 2.68e-61: 208: 29.71
+	Ss
		1122361 Q55942_SYNY3 (2-228): 1.03e-64: 202: 32.76		Q55941_SYNY3 (218-457): 1.02e-62: 211: 28.52
+	Ec
		439475 PHOB_ECOLI (3-231): 2.91e-70: 216: 38.20		PHOR_ECOLI (180-452): 1.78e-57: 197: 25.36
+	Mx
		1091248 Q1D1K9_MYXXD (3-231): 3.51e-67: 208: 42.61		Q1CVV2_MYXXD (213-451): 8.42e-57: 203: 26.51
+	Mx
		1091327 Q1D8M8_MYXXD (4-232): 5.29e-64: 200: 37.07		Q1CWW4_MYXXD (127-454): 4.57e-59: 208: 21.73
+	Mx
		1091452 Q1D4T4_MYXXD (2-230): 2.19e-68: 211: 36.09		Q1D1W0_MYXXD (159-450): 4.99e-57: 197: 26.87
+	Mx
		1091475 Q1D8M8_MYXXD (4-232): 5.29e-64: 200: 37.07		Q1D333_MYXXD (227-457): 2.68e-61: 208: 29.71
+	Cv
		1308005 Q9ABD5_CAUVC (4-232): 1.4e-67: 209: 39.06		Q9ABD9_CAUVC (227-455): 6.88e-58: 199: 24.15
+	Ec
		465607 OMPR_ECOLI (3-231): 5.76e-67: 208: 38.53		ENVZ_ECOLI (158-454): 3.38e-57: 197: 28.28
+	Mx
		1091457 Q1D8M8_MYXXD (4-232): 5.29e-64: 200: 37.07		Q1D1W0_MYXXD (159-450): 4.99e-57: 197: 26.87
+	Mx
		1091565 Q1DCL7_MYXXD (4-229): 5.41e-71: 218: 38.16		Q1D948_MYXXD (242-453): 2.12e-13: 74.7: 30.47
+	Ss
		939460 P74626_SYNY3 (2-229): 2.11e-67: 209: 33.48		P74622_SYNY3 (231-454): 1.78e-15: 78.6: 27.60
+	Mx
		1091496 Q1D4T4_MYXXD (2-230): 2.19e-68: 211: 36.09		Q1D4T3_MYXXD (217-429): 1.24e-13: 74.7: 27.68
+	Mx
		1091501 Q1D4T4_MYXXD (2-230): 2.19e-68: 211: 36.09		Q1D948_MYXXD (242-453): 2.12e-13: 74.7: 30.47
+	Ec
		602045 KDPE_ECOLI (1-228): 6.43e-66: 205: 30.57		KDPD_ECOLI (200-452): 1.4e-14: 78.2: 30.40