HitPredict

Interactor 1: UPP2 (O95045)
Uridine phosphorylase 2 (UPase 2) (UrdPase 2) (EC 2.4.2.3)
Gene: UPP2

Interactor 2: SIAH1 (Q8IUQ4)
E3 ubiquitin-protein ligase SIAH1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH1) (Seven in absentia homolog 1) (Siah-1) (Siah-1a)
Gene: SIAH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	25416956, 26871637
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 282
+	Hs
		3496 A0A0S2Z6U5_HUMAN (1-271): 3.9e-137: 391: 100.00		SIAH1_HUMAN (1-282): 7.29e-121: 348: 100.00
+	Hs
		3450 A0A0S2Z639_HUMAN (1-62): 1.03e-32: 117: 96.77		SIAH1_HUMAN (1-282): 7.29e-121: 348: 100.00