HitPredict

Interactor 1: ZO3 (O95049)
Tight junction protein ZO-3 (Tight junction protein 3) (Zona occludens protein 3) (Zonula occludens protein 3)
Gene: TJP3

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35063084
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 919 Hs			1 758
+	Hs
		496912 ZO1_HUMAN (1-907): 7.48e-134: 442: 39.53		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497003 MPP2_HUMAN (321-774): 6.34e-98: 320: 16.05		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		159141 CSKP_HUMAN (113-775): 1.45e-79: 279: 14.38		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496940 DLG1_HUMAN (2-280): 2.51e-31: 134: 17.54		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497733 ZO2_HUMAN (349-656): 8.12e-11: 68.3: 16.32		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497866 GRIP1_HUMAN (3-133): 7.46e-11: 68.3: 16.54		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Mm
		581224 DLG4_MOUSE (325-463): 1.89e-12: 73.3: 17.01		NFH_MOUSE (284-730): 4.84e-16: 84.7: 14.99
+	Mm
		88458 DLG4_MOUSE (325-463): 1.89e-12: 73.3: 17.01		D3Z656_MOUSE (72-555): 1.33e-11: 70.4: 11.56
+	Mm
		1143433 DLG4_MOUSE (325-463): 1.89e-12: 73.3: 17.01		SYNJ1_MOUSE (129-637): 3.11e-11: 69.3: 11.20
+	Ce
		103468 DLG1_CAEEL (236-467): 6.83e-11: 68.3: 13.77		TTN1_CAEEL (4-632): 3.28e-10: 66.1: 11.61