HitPredict

Interactor 1: REC8 (O95072)
Meiotic recombination protein REC8 homolog (Cohesin Rec8p)
Gene: REC8

Interactor 2: SMC3 (Q9UQE7)
Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3) (Basement membrane-associated chondroitin proteoglycan) (Bamacan) (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP)
Gene: SMC3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.861

The method score is based on:

Property Details
Experiments 12759374, 24981860, 33961781
Identification Methods affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Rad21_Rec8~SMC_N, Rad21_Rec8_N~SMC_N
Common GO terms GO:0000800 - lateral element
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0007062 - sister chromatid cohesion
GO:0008278 - cohesin complex
and 2 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 547
Hs

1 1217
+ Mm
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024