Interactor 1: MFN2 (O95140)
Mitofusin-2 (EC 3.6.5.-) (Transmembrane GTPase MFN2)
Gene: MFN2

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.44 0.60 0.515

The method score is based on:

Property Details
Experiments 24282027
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol
and 1 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 757
Hs

1 2527
+ Hs
+ Hs

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Last updated: 15 Jul 2024