Interactor 1: ARK73 (O95154)
Aflatoxin B1 aldehyde reductase member 3 (EC 1.-.-.-) (AFB1 aldehyde reductase 2) (AFB1-AR 2)
Gene: AKR7A3

Interactor 2: ARK73 (O95154)
Aflatoxin B1 aldehyde reductase member 3 (EC 1.-.-.-) (AFB1 aldehyde reductase 2) (AFB1-AR 2)
Gene: AKR7A3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.927

The method score is based on:

Property Details
Experiments 25416956, 16189514, 32296183, 31515488, unassigned1304
Identification Methods two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Aldo_ket_red~Aldo_ket_red
Common GO terms GO:0004033 - aldo-keto reductase (NADPH) activity
GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol
GO:0006081 - cellular aldehyde metabolic process
and 2 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 331
Hs

1 331
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024