HitPredict

Interactor 1: UBE4B (O95155)
Ubiquitin conjugation factor E4 B (EC 2.3.2.27) (Homozygously deleted in neuroblastoma 1) (RING-type E3 ubiquitin transferase E4 B) (Ubiquitin fusion degradation protein 2)
Gene: UBE4B

Interactor 2: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.705

Property	Details
Experiments	26673821, 36865087, 21317885, 24587254
Identification Methods	affinity chromatography technology, enzymatic study, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0019899 - enzyme binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1302 Hs			1 393
+	Hs
		175801 UBE4B_HUMAN (1-1302): 0: 1721: 100.00		P73_HUMAN (13-362): 2.35e-166: 481: 39.74
+	Hs
		305197 UBE4B_HUMAN (1-1302): 0: 1721: 100.00		P63_HUMAN (28-363): 2.35e-145: 429: 42.11
+	Hs
		386715 UBE4A_HUMAN (390-1298): 0: 795: 25.65		P53_HUMAN (1-393): 0: 619: 100.00
+	Hs
		387740 CHIP_HUMAN (1040-1301): 3.36e-55: 196: 16.18		P53_HUMAN (1-393): 0: 619: 100.00
+	Hs
		1093063 CHIP_HUMAN (1040-1301): 3.36e-55: 196: 16.18		Q1MSW8_HUMAN (1-331): 0: 517: 99.70
+	Hs
		175941 CHIP_HUMAN (1040-1301): 3.36e-55: 196: 16.18		P73_HUMAN (13-362): 2.35e-166: 481: 39.74
+	Hs
		1330014 CHIP_HUMAN (1040-1301): 3.36e-55: 196: 16.18		P63_HUMAN (28-363): 2.35e-145: 429: 42.11