Interactor 1: UBE4B (O95155)
Ubiquitin conjugation factor E4 B (EC 2.3.2.27) (Homozygously deleted in neuroblastoma 1) (RING-type E3 ubiquitin transferase E4 B) (Ubiquitin fusion degradation protein 2)
Gene: UBE4B

Interactor 2: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.757

The method score is based on:

Property Details
Experiments 29599191, 14749733, 21282470, 18022694, 20414249, 26389662, 27226613, 28514442, 33961781, 19175675, 26712280
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0036503 - ERAD pathway
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1302
Hs

1 806
+ Sc
+ Ce
+ Ce
+ Hs
+ Rn
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024