HitPredict

Interactor 1: NXPH2 (O95156)
Neurexophilin-2
Gene: NXPH2

Interactor 2: FRAS1 (Q86XX4)
Extracellular matrix organizing protein FRAS1 (Fraser syndrome 1 protein)
Gene: FRAS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	26186194, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 264 Hs			1 4008
+	Hs
		305272 NXPH3_HUMAN (90-264): 1.46e-105: 308: 63.43		FRAS1_HUMAN (1-4008): 0: 2806: 100.00
+	Hs
		305219 NXPH2_HUMAN (1-264): 0: 520: 100.00		FREM2_HUMAN (1296-3338): 2.12e-108: 393: 18.62
+	Hs
		305215 NXPH2_HUMAN (1-264): 0: 520: 100.00		PCDH1_HUMAN (2678-3411): 7.66e-49: 194: 10.88
+	Hs
		305227 NXPH2_HUMAN (1-264): 0: 520: 100.00		AGRV1_HUMAN (1121-3205): 1.27e-35: 153: 12.28
+	Hs
		885691 NXPH1_HUMAN (76-264): 5.26e-128: 365: 80.95		CSPG4_HUMAN (1594-2898): 4.17e-72: 273: 17.50
+	Hs
		305216 NXPH2_HUMAN (1-264): 0: 520: 100.00		FAT1_HUMAN (208-422): 2.76e-12: 75.8: 10.19
+	Hs
		305230 NXPH2_HUMAN (1-264): 0: 520: 100.00		CELR2_HUMAN (985-1093): 1.37e-10: 70.4: 16.36
+	Hs
		305221 NXPH2_HUMAN (1-264): 0: 520: 100.00		FAT4_HUMAN (2-88): 4.91e-10: 68.5: 9.89
+	Hs
		305231 NXPH2_HUMAN (1-264): 0: 520: 100.00		CELR1_HUMAN (213-451): 3.32e-09: 65.8: 12.20
+	Hs
		305267 NXPH3_HUMAN (90-264): 1.46e-105: 308: 63.43		CSPG4_HUMAN (1594-2898): 4.17e-72: 273: 17.50
+	Hs
		885685 NXPH1_HUMAN (76-264): 5.26e-128: 365: 80.95		PCDH1_HUMAN (2678-3411): 7.66e-49: 194: 10.88
+	Hs
		305254 NXPH3_HUMAN (90-264): 1.46e-105: 308: 63.43		PCDH1_HUMAN (2678-3411): 7.66e-49: 194: 10.88
+	Hs
		305283 NXPH3_HUMAN (90-264): 1.46e-105: 308: 63.43		CELR2_HUMAN (985-1093): 1.37e-10: 70.4: 16.36
+	Hs
		305284 NXPH3_HUMAN (90-264): 1.46e-105: 308: 63.43		CELR1_HUMAN (213-451): 3.32e-09: 65.8: 12.20