HitPredict

Interactor 1: GBRAP (O95166)
Gamma-aminobutyric acid receptor-associated protein (GABA(A) receptor-associated protein) (MM46)
Gene: GABARAP

Interactor 2: M4K2 (Q12851)
Mitogen-activated protein kinase kinase kinase kinase 2 (EC 2.7.11.1) (B lymphocyte serine/threonine-protein kinase) (Germinal center kinase) (GC kinase) (MAPK/ERK kinase kinase kinase 2) (MEK kinase kinase 2) (MEKKK 2) (Rab8-interacting protein)
Gene: MAP4K2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	32640226
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 820
+	Hs
		891114 GBRL2_HUMAN (1-117): 2.75e-58: 176: 57.27		M4K2_HUMAN (1-820): 0: 877: 100.00
+	Hs
		1018189 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		M4K2_HUMAN (1-820): 0: 877: 100.00
+	Hs
		891118 GBRL2_HUMAN (1-117): 2.75e-58: 176: 57.27		STK4_HUMAN (3-421): 9.45e-121: 375: 33.89
+	Hs
		306146 GBRAP_HUMAN (1-117): 8.06e-57: 173: 100.00		STK4_HUMAN (3-421): 9.45e-121: 375: 33.89
+	Hs
		1023108 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		STK4_HUMAN (3-421): 9.45e-121: 375: 33.89
+	Hs
		891124 GBRL2_HUMAN (1-117): 2.75e-58: 176: 57.27		STK3_HUMAN (3-291): 1.2e-118: 369: 43.10
+	Hs
		306153 GBRAP_HUMAN (1-117): 8.06e-57: 173: 100.00		STK3_HUMAN (3-291): 1.2e-118: 369: 43.10
+	Hs
		1027427 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		STK3_HUMAN (3-291): 1.2e-118: 369: 43.10
+	Hs
		1023110 MLP3A_HUMAN (5-117): 2.29e-45: 144: 30.44		STK4_HUMAN (3-421): 9.45e-121: 375: 33.89
+	Hs
		1023104 MLP3C_HUMAN (5-116): 1.15e-44: 143: 38.60		STK4_HUMAN (3-421): 9.45e-121: 375: 33.89
+	Hs
		1023105 MLP3B_HUMAN (2-117): 3.54e-44: 141: 30.51		STK4_HUMAN (3-421): 9.45e-121: 375: 33.89
+	Hs
		1027430 MLP3A_HUMAN (5-117): 2.29e-45: 144: 30.44		STK3_HUMAN (3-291): 1.2e-118: 369: 43.10
+	Hs
		1027422 MLP3C_HUMAN (5-116): 1.15e-44: 143: 38.60		STK3_HUMAN (3-291): 1.2e-118: 369: 43.10
+	Hs
		1027423 MLP3B_HUMAN (2-117): 3.54e-44: 141: 30.51		STK3_HUMAN (3-291): 1.2e-118: 369: 43.10
+	Hs
		306314 GBRAP_HUMAN (1-117): 8.06e-57: 173: 100.00		SLK_HUMAN (11-274): 1.96e-66: 242: 45.32
+	Hs
		296420 MLP3A_HUMAN (5-117): 2.29e-45: 144: 30.44		STK10_HUMAN (11-289): 8.66e-66: 238: 43.26