HitPredict

Interactor 1: GBRAP (O95166)
Gamma-aminobutyric acid receptor-associated protein (GABA(A) receptor-associated protein) (MM46)
Gene: GABARAP

Interactor 2: TBC15 (Q8TC07)
TBC1 domain family member 15 (GTPase-activating protein RAB7) (GAP for RAB7) (Rab7-GAP)
Gene: TBC1D15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.50	0.535

Property	Details
Experiments	20562859
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 117 Hs			1 691
+	Hs
		891232 GBRL2_HUMAN (1-117): 2.75e-58: 176: 57.27		TBC15_HUMAN (1-691): 0: 692: 100.00
+	Hs
		1253208 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		TBC15_HUMAN (1-691): 0: 692: 100.00
+	Hs
		1328034 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		TBC17_HUMAN (1-644): 1.78e-176: 519: 47.45
+	Dm
		1364630 Q9VEG5_DROME (1-116): 5.35e-54: 166: 77.59		Q9VPL5_DROME (8-629): 2.78e-132: 408: 31.81
+	Hs
		891174 GBRL2_HUMAN (1-117): 2.75e-58: 176: 57.27		TBC25_HUMAN (308-559): 4.74e-89: 294: 37.95
+	Hs
		306201 GBRAP_HUMAN (1-117): 8.06e-57: 173: 100.00		TBC25_HUMAN (308-559): 4.74e-89: 294: 37.95
+	Hs
		1109690 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		TBC25_HUMAN (308-559): 4.74e-89: 294: 37.95
+	Hs
		1252977 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		TBC16_HUMAN (271-667): 1.46e-87: 292: 28.88
+	Hs
		891183 GBRL2_HUMAN (1-117): 2.75e-58: 176: 57.27		TBC9B_HUMAN (196-671): 5.6e-80: 279: 14.85
+	Hs
		891196 GBRL2_HUMAN (1-117): 2.75e-58: 176: 57.27		TBCD9_HUMAN (196-659): 2.96e-80: 279: 13.53
+	Hs
		1117430 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		TB10B_HUMAN (212-670): 5.71e-83: 281: 15.92
+	Hs
		1146079 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		TBC9B_HUMAN (196-671): 5.6e-80: 279: 14.85
+	Hs
		1170417 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		TBCD9_HUMAN (196-659): 2.96e-80: 279: 13.53
+	Sc
		746044 ATG8_YEAST (1-116): 9.18e-59: 178: 55.17		GYP1_YEAST (285-557): 1.13e-79: 268: 22.85
+	Hs
		1109691 MLP3A_HUMAN (5-117): 2.29e-45: 144: 30.44		TBC25_HUMAN (308-559): 4.74e-89: 294: 37.95
+	Hs
		1198509 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		TBCD1_HUMAN (198-649): 1.54e-76: 268: 17.92
+	Hs
		1315253 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		TB10A_HUMAN (254-681): 2.44e-80: 266: 18.40
+	Hs
		1117431 MLP3A_HUMAN (5-117): 2.29e-45: 144: 30.44		TB10B_HUMAN (212-670): 5.71e-83: 281: 15.92
+	Hs
		1146080 MLP3A_HUMAN (5-117): 2.29e-45: 144: 30.44		TBC9B_HUMAN (196-671): 5.6e-80: 279: 14.85
+	Hs
		1170419 MLP3A_HUMAN (5-117): 2.29e-45: 144: 30.44		TBCD9_HUMAN (196-659): 2.96e-80: 279: 13.53