HitPredict

Interactor 1: GBRAP (O95166)
Gamma-aminobutyric acid receptor-associated protein (GABA(A) receptor-associated protein) (MM46)
Gene: GABARAP

Interactor 2: RBCC1 (Q8TDY2)
RB1-inducible coiled-coil protein 1 (FAK family kinase-interacting protein of 200 kDa) (FIP200)
Gene: RB1CC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.655

Property	Details
Experiments	28253953, 23043107, 20562859
Identification Methods	pull down, affinity chromatography technology, unspecified method, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000045 - autophagosome assembly GO:0000421 - autophagosome membrane GO:0005764 - lysosome GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 1594
+	Hs
		891236 GBRL2_HUMAN (1-117): 2.75e-58: 176: 57.27		RBCC1_HUMAN (1-1594): 9.92e-159: 526: 100.00
+	Hs
		1255687 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		RBCC1_HUMAN (1-1594): 9.92e-159: 526: 100.00
+	Hs
		1255690 MLP3A_HUMAN (5-117): 2.29e-45: 144: 30.44		RBCC1_HUMAN (1-1594): 9.92e-159: 526: 100.00
+	Hs
		1255678 MLP3C_HUMAN (5-116): 1.15e-44: 143: 38.60		RBCC1_HUMAN (1-1594): 9.92e-159: 526: 100.00
+	Hs
		1255684 MLP3B_HUMAN (2-117): 3.54e-44: 141: 30.51		RBCC1_HUMAN (1-1594): 9.92e-159: 526: 100.00
+	Ce
		999347 LGG1_CAEEL (1-116): 2.47e-55: 170: 83.62		Q22342_CAEEL (276-1120): 2.05e-63: 240: 15.60
+	Hs
		725011 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		MYH9_HUMAN (1067-1588): 1.89e-22: 107: 11.48
+	Hs
		551651 GBRL2_HUMAN (1-117): 2.75e-58: 176: 57.27		DESP_HUMAN (899-1502): 4.19e-13: 77.2: 12.32
+	Hs
		305947 GBRAP_HUMAN (1-117): 8.06e-57: 173: 100.00		DESP_HUMAN (899-1502): 4.19e-13: 77.2: 12.32
+	Hs
		551832 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		DESP_HUMAN (899-1502): 4.19e-13: 77.2: 12.32
+	Hs
		1068658 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		PLEC_HUMAN (101-713): 3.96e-12: 74.1: 7.02
+	Hs
		551835 MLP3A_HUMAN (5-117): 2.29e-45: 144: 30.44		DESP_HUMAN (899-1502): 4.19e-13: 77.2: 12.32
+	Hs
		551829 MLP3B_HUMAN (2-117): 3.54e-44: 141: 30.51		DESP_HUMAN (899-1502): 4.19e-13: 77.2: 12.32
+	Hs
		1068655 MLP3B_HUMAN (2-117): 3.54e-44: 141: 30.51		PLEC_HUMAN (101-713): 3.96e-12: 74.1: 7.02