HitPredict

Interactor 1: GBRAP (O95166)
Gamma-aminobutyric acid receptor-associated protein (GABA(A) receptor-associated protein) (MM46)
Gene: GABARAP

Interactor 2: FAN (Q92636)
Protein FAN (Factor associated with neutral sphingomyelinase activation) (Factor associated with N-SMase activation)
Gene: NSMAF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.550

Property	Details
Experiments	20562859
Identification Methods	pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 917
+	Hs
		891255 GBRL2_HUMAN (1-117): 2.75e-58: 176: 57.27		FAN_HUMAN (1-917): 0: 813: 100.00
+	Hs
		1268699 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		FAN_HUMAN (1-917): 0: 813: 100.00
+	Hs
		1268700 MLP3A_HUMAN (5-117): 2.29e-45: 144: 30.44		FAN_HUMAN (1-917): 0: 813: 100.00
+	Hs
		1268697 MLP3C_HUMAN (5-116): 1.15e-44: 143: 38.60		FAN_HUMAN (1-917): 0: 813: 100.00
+	Hs
		1268698 MLP3B_HUMAN (2-117): 3.54e-44: 141: 30.51		FAN_HUMAN (1-917): 0: 813: 100.00
+	Hs
		891218 GBRL2_HUMAN (1-117): 2.75e-58: 176: 57.27		WDFY3_HUMAN (87-893): 7.02e-164: 533: 24.22
+	Hs
		1152287 Q6IAW1_HUMAN (1-117): 8.06e-57: 173: 100.00		WDFY3_HUMAN (87-893): 7.02e-164: 533: 24.22
+	Hs
		306231 GBRAP_HUMAN (1-117): 8.06e-57: 173: 100.00		WDFY3_HUMAN (87-893): 7.02e-164: 533: 24.22
+	Hs
		1224700 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		WDFY3_HUMAN (87-893): 7.02e-164: 533: 24.22
+	Hs
		1224703 MLP3A_HUMAN (5-117): 2.29e-45: 144: 30.44		WDFY3_HUMAN (87-893): 7.02e-164: 533: 24.22
+	Hs
		1224697 MLP3C_HUMAN (5-116): 1.15e-44: 143: 38.60		WDFY3_HUMAN (87-893): 7.02e-164: 533: 24.22
+	Hs
		1224698 MLP3B_HUMAN (2-117): 3.54e-44: 141: 30.51		WDFY3_HUMAN (87-893): 7.02e-164: 533: 24.22
+	Mm
		1167198 MLP3A_MOUSE (5-117): 2.29e-45: 144: 30.44		WDFY3_MOUSE (87-793): 1.99e-155: 509: 24.44
+	Hs
		891030 GBRL2_HUMAN (1-117): 2.75e-58: 176: 57.27		WDR5_HUMAN (743-915): 1.38e-54: 194: 19.89
+	Dm
		1370863 Q9W2S2_DROME (1-117): 5.29e-58: 176: 91.45		Q9VML2_DROME (725-917): 4.02e-24: 112: 14.62
+	Hs
		842026 MLP3B_HUMAN (2-117): 3.54e-44: 141: 30.51		LRBA_HUMAN (539-845): 1.89e-27: 122: 13.46
+	Hs
		1122381 MLP3C_HUMAN (5-116): 1.15e-44: 143: 38.60		WDR81_HUMAN (300-576): 8.71e-22: 104: 30.07
+	Hs
		1326179 MLP3B_HUMAN (2-117): 3.54e-44: 141: 30.51		NLE1_HUMAN (454-574): 1.09e-09: 63.9: 9.52