HitPredict

Interactor 1: GBRAP (O95166)
Gamma-aminobutyric acid receptor-associated protein (GABA(A) receptor-associated protein) (MM46)
Gene: GABARAP

Interactor 2: RETR1 (Q9H6L5)
Reticulophagy regulator 1 (Reticulophagy receptor 1)
Gene: RETREG1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.50	0.626

Property	Details
Experiments	29867141, 31006538, 32620754, 26040720
Identification Methods	pull down, affinity chromatography technology, unspecified method, x-ray crystallography
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 117 Hs			1 497
+	Hs
		891323 GBRL2_HUMAN (1-117): 2.75e-58: 176: 57.27		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		1328030 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Mm
		1257559 MLP3B_MOUSE (2-116): 2.1e-44: 142: 30.77		RETR1_MOUSE (1-497): 0: 767: 87.32
+	Hs
		1330625 MLP3A_HUMAN (5-117): 2.29e-45: 144: 30.44		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		1326146 MLP3B_HUMAN (2-117): 3.54e-44: 141: 30.51		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		61903 MP3B2_HUMAN (2-117): 2.36e-43: 139: 29.66		RETR1_HUMAN (1-497): 0: 753: 100.00
+	Hs
		891208 GBRL2_HUMAN (1-117): 2.75e-58: 176: 57.27		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		306223 GBRAP_HUMAN (1-117): 8.06e-57: 173: 100.00		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1202377 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1202382 MLP3A_HUMAN (5-117): 2.29e-45: 144: 30.44		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		1202374 MLP3B_HUMAN (2-117): 3.54e-44: 141: 30.51		RETR3_HUMAN (19-467): 0: 601: 35.90
+	Hs
		306234 GBRAP_HUMAN (1-117): 8.06e-57: 173: 100.00		RETR2_HUMAN (77-472): 2.56e-164: 477: 28.57
+	Hs
		1240861 GBRL1_HUMAN (1-116): 8.15e-56: 170: 87.07		RETR2_HUMAN (77-472): 2.56e-164: 477: 28.57
+	Hs
		1240862 MLP3A_HUMAN (5-117): 2.29e-45: 144: 30.44		RETR2_HUMAN (77-472): 2.56e-164: 477: 28.57
+	Hs
		1240860 MLP3B_HUMAN (2-117): 3.54e-44: 141: 30.51		RETR2_HUMAN (77-472): 2.56e-164: 477: 28.57