HitPredict

Interactor 1: VAMP5 (O95183)
Vesicle-associated membrane protein 5 (VAMP-5) (Myobrevin)
Gene: VAMP5

Interactor 2: NSF (P46459)
Vesicle-fusing ATPase (EC 3.6.4.6) (N-ethylmaleimide-sensitive fusion protein) (NEM-sensitive fusion protein) (Vesicular-fusion protein NSF)
Gene: NSF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	30833792
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0043001 - Golgi to plasma membrane protein transport
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 116 Hs			1 744
+	Hs
		261641 VAMP4_HUMAN (3-73): 1.13e-25: 95.3: 29.58		NSF_HUMAN (1-744): 0: 572: 100.00
+	Hs
		803966 VAMP8_HUMAN (2-74): 9.04e-26: 94.2: 26.03		NSF_HUMAN (1-744): 0: 572: 100.00
+	Hs
		803893 VAMP2_HUMAN (2-75): 2.33e-25: 93.8: 39.19		NSF_HUMAN (1-744): 0: 572: 100.00
+	Hs
		263192 SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65		NSF_HUMAN (1-744): 0: 572: 100.00
+	Hs
		803923 VAMP3_HUMAN (2-72): 2.01e-24: 90.7: 38.03		NSF_HUMAN (1-744): 0: 572: 100.00
+	Dm
		870075 Q7JYX5_DROME (4-96): 1.36e-32: 114: 31.18		NSF2_DROME (5-742): 6.55e-166: 498: 63.21
+	Sc
		578512 SNC1_YEAST (2-72): 1.48e-23: 89.2: 21.13		SEC18_YEAST (4-721): 5.88e-146: 447: 44.22
+	Hs
		874800 VAMP2_HUMAN (2-75): 2.33e-25: 93.8: 39.19		TERA_HUMAN (146-479): 5.59e-69: 244: 31.05
+	Hs
		263204 SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65		TERA_HUMAN (146-479): 5.59e-69: 244: 31.05