HitPredict

Interactor 1: VAMP5 (O95183)
Vesicle-associated membrane protein 5 (VAMP-5) (Myobrevin)
Gene: VAMP5

Interactor 2: STX12 (Q86Y82)
Syntaxin-12
Gene: STX12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	30833792, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNARE~Synaptobrevin
Common GO terms	GO:0005794 - Golgi apparatus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 116 Hs			1 276
+	Hs
		306784 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		STX1B_HUMAN (4-273): 3.79e-67: 212: 23.19
+	Hs
		306800 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		STX1A_HUMAN (17-273): 6.81e-67: 211: 23.19
+	Hs
		306763 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		STX2_HUMAN (16-272): 3.38e-66: 209: 26.62
+	Dm
		1098086 Q7JYX5_DROME (4-96): 1.36e-32: 114: 31.18		STX1A_DROME (4-273): 6.4e-64: 204: 22.10
+	At
		955681 VA713_ARATH (4-91): 1.44e-32: 114: 22.73		SYP22_ARATH (1-258): 1.52e-59: 191: 24.43
+	Hs
		152122 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		STX16_HUMAN (6-250): 1.6e-56: 186: 25.00
+	At
		955702 VA721_ARATH (5-92): 9.82e-32: 113: 26.14		SYP22_ARATH (1-258): 1.52e-59: 191: 24.43
+	At
		249598 VA721_ARATH (5-92): 9.82e-32: 113: 26.14		SYP41_ARATH (2-273): 4.62e-58: 189: 21.07
+	At
		1352937 VA721_ARATH (5-92): 9.82e-32: 113: 26.14		SY122_ARATH (1-252): 6.92e-57: 187: 20.53
+	Hs
		178339 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		STX7_HUMAN (8-272): 1.12e-55: 181: 51.70
+	At
		1352876 VA721_ARATH (5-92): 9.82e-32: 113: 26.14		SYP43_ARATH (2-273): 2.11e-55: 183: 20.00
+	Hs
		306789 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		STX4_HUMAN (6-272): 1.25e-53: 177: 24.27
+	Hs
		306792 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		STX3_HUMAN (5-250): 2.56e-53: 176: 25.20
+	Dm
		1178101 Q7JYX5_DROME (4-96): 1.36e-32: 114: 31.18		Q7K0X9_DROME (21-274): 3.74e-54: 178: 31.84
+	Hs
		306896 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		X5D7S1_HUMAN (17-272): 5.04e-53: 174: 21.01
+	At
		1114744 VA721_ARATH (5-92): 9.82e-32: 113: 26.14		SY111_ARATH (4-252): 1.64e-51: 172: 19.77
+	Hs
		69711 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		B1AJQ6_HUMAN (1-192): 1.13e-50: 167: 88.84
+	Dm
		1178134 Q7JYX5_DROME (4-96): 1.36e-32: 114: 31.18		Q9VU45_DROME (13-269): 2.95e-49: 166: 28.41
+	At
		1258650 VA721_ARATH (5-92): 9.82e-32: 113: 26.14		SY132_ARATH (107-252): 5.34e-12: 66.6: 32.88
+	Dm
		1178130 Q7JYX5_DROME (4-96): 1.36e-32: 114: 31.18		Q9VR90_DROME (166-256): 7.07e-11: 63.5: 36.26