HitPredict

Interactor 1: VAMP5 (O95183)
Vesicle-associated membrane protein 5 (VAMP-5) (Myobrevin)
Gene: VAMP5

Interactor 2: ERGI2 (Q96RQ1)
Endoplasmic reticulum-Golgi intermediate compartment protein 2
Gene: ERGIC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 116 Hs			1 377
+	Hs
		261709 VAMP4_HUMAN (3-73): 1.13e-25: 95.3: 29.58		ERGI2_HUMAN (1-377): 7.64e-177: 498: 100.00
+	Hs
		263331 SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65		ERGI2_HUMAN (1-377): 7.64e-177: 498: 100.00
+	Hs
		306892 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		ERGI3_HUMAN (8-351): 1.71e-142: 411: 29.32
+	Hs
		261742 VAMP4_HUMAN (3-73): 1.13e-25: 95.3: 29.58		ERGI3_HUMAN (8-351): 1.71e-142: 411: 29.32
+	Hs
		620292 VAMP1_HUMAN (2-78): 6.73e-26: 95: 36.36		ERGI3_HUMAN (8-351): 1.71e-142: 411: 29.32
+	Hs
		926269 VAMP2_HUMAN (2-75): 2.33e-25: 93.8: 39.19		ERGI3_HUMAN (8-351): 1.71e-142: 411: 29.32
+	Hs
		263395 SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65		ERGI3_HUMAN (8-351): 1.71e-142: 411: 29.32
+	Hs
		1079471 VAMP3_HUMAN (2-72): 2.01e-24: 90.7: 38.03		ERGI3_HUMAN (8-351): 1.71e-142: 411: 29.32
+	Hs
		926241 VAMP2_HUMAN (2-75): 2.33e-25: 93.8: 39.19		ERGI1_HUMAN (14-351): 5.69e-90: 274: 19.83
+	Hs
		263316 SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65		ERGI1_HUMAN (14-351): 5.69e-90: 274: 19.83
+	Hs
		1079395 VAMP3_HUMAN (2-72): 2.01e-24: 90.7: 38.03		ERGI1_HUMAN (14-351): 5.69e-90: 274: 19.83
+	Zm
		31306 A0A1D6KH00_MAIZE (5-91): 6.6e-34: 125: 28.74		Q5EUD1_MAIZE (11-138): 3.33e-26: 111: 25.19