HitPredict

Interactor 1: VAMP5 (O95183)
Vesicle-associated membrane protein 5 (VAMP-5) (Myobrevin)
Gene: VAMP5

Interactor 2: SNAB (Q9H115)
Beta-soluble NSF attachment protein (SNAP-beta) (N-ethylmaleimide-sensitive factor attachment protein beta)
Gene: NAPB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	SNAP~Synaptobrevin
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 116 Hs			1 298
+	Hs
		306778 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		SNAA_HUMAN (1-293): 7.24e-109: 319: 83.96
+	Hs
		261720 VAMP4_HUMAN (3-73): 1.13e-25: 95.3: 29.58		SNAB_HUMAN (1-298): 3.42e-116: 338: 100.00
+	Mm
		659546 VAMP2_MOUSE (2-75): 2.33e-25: 93.8: 39.19		SNAB_MOUSE (1-298): 3.42e-116: 338: 100.00
+	Dm
		1095560 Q7JYX5_DROME (4-96): 1.36e-32: 114: 31.18		SNAP_DROME (5-292): 1.02e-103: 306: 62.15
+	Hs
		850546 VAMP7_HUMAN (4-96): 5.88e-26: 98: 31.18		SNAA_HUMAN (1-293): 7.24e-109: 319: 83.96
+	Hs
		261646 VAMP4_HUMAN (3-73): 1.13e-25: 95.3: 29.58		SNAA_HUMAN (1-293): 7.24e-109: 319: 83.96
+	Hs
		873576 VAMP8_HUMAN (2-74): 9.04e-26: 94.2: 26.03		SNAA_HUMAN (1-293): 7.24e-109: 319: 83.96
+	Hs
		873528 VAMP2_HUMAN (2-75): 2.33e-25: 93.8: 39.19		SNAA_HUMAN (1-293): 7.24e-109: 319: 83.96
+	Dm
		577215 SYB_DROME (2-88): 9.74e-30: 105: 39.08		SNAP_DROME (5-292): 1.02e-103: 306: 62.15
+	Hs
		263203 SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65		SNAA_HUMAN (1-293): 7.24e-109: 319: 83.96
+	Zm
		31296 A0A1D6KH00_MAIZE (5-91): 6.6e-34: 125: 28.74		A0A1D6PZ82_MAIZE (5-272): 1.43e-88: 269: 37.55
+	Hs
		306855 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		SNAG_HUMAN (4-251): 6.3e-69: 218: 24.30
+	Hs
		850592 VAMP7_HUMAN (4-96): 5.88e-26: 98: 31.18		SNAG_HUMAN (4-251): 6.3e-69: 218: 24.30
+	Hs
		261710 VAMP4_HUMAN (3-73): 1.13e-25: 95.3: 29.58		SNAG_HUMAN (4-251): 6.3e-69: 218: 24.30
+	Hs
		1306201 VAMP8_HUMAN (2-74): 9.04e-26: 94.2: 26.03		SNAG_HUMAN (4-251): 6.3e-69: 218: 24.30
+	Hs
		926249 VAMP2_HUMAN (2-75): 2.33e-25: 93.8: 39.19		SNAG_HUMAN (4-251): 6.3e-69: 218: 24.30
+	Hs
		263338 SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65		SNAG_HUMAN (4-251): 6.3e-69: 218: 24.30
+	Dm
		1178116 Q7JYX5_DROME (4-96): 1.36e-32: 114: 31.18		Q9U6R9_DROME (4-265): 3.27e-59: 193: 19.70
+	Dm
		577238 SYB_DROME (2-88): 9.74e-30: 105: 39.08		Q9U6R9_DROME (4-265): 3.27e-59: 193: 19.70
+	Dm
		1178122 Q7JYX5_DROME (4-96): 1.36e-32: 114: 31.18		Q9VH25_DROME (42-265): 8.61e-52: 173: 19.03