HitPredict

Interactor 1: VAMP5 (O95183)
Vesicle-associated membrane protein 5 (VAMP-5) (Myobrevin)
Gene: VAMP5

Interactor 2: VPS45 (Q9NRW7)
Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45)
Gene: VPS45

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	30833792, 33961781
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005794 - Golgi apparatus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 116 Hs			1 570
+	Hs
		261727 VAMP4_HUMAN (3-73): 1.13e-25: 95.3: 29.58		VPS45_HUMAN (1-570): 0: 647: 100.00
+	Hs
		1079449 VAMP3_HUMAN (2-72): 2.01e-24: 90.7: 38.03		VPS45_HUMAN (1-570): 0: 647: 100.00
+	At
		1319859 VA721_ARATH (5-92): 9.82e-32: 113: 26.14		KEULE_ARATH (8-562): 1.04e-156: 465: 21.14
+	Hs
		119628 VAMP2_HUMAN (2-75): 2.33e-25: 93.8: 39.19		STXB3_HUMAN (22-552): 9.03e-161: 473: 19.44
+	Dm
		1096640 Q7JYX5_DROME (4-96): 1.36e-32: 114: 31.18		SLY1_DROME (1-556): 1.77e-145: 435: 20.44
+	Hs
		306839 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		SCFD1_HUMAN (18-553): 2.28e-141: 425: 20.10
+	Sc
		704514 SNC2_YEAST (2-74): 6.15e-24: 90: 23.29		VPS45_YEAST (1-549): 3.04e-152: 451: 36.33
+	Dm
		577216 SYB_DROME (2-88): 9.74e-30: 105: 39.08		SLY1_DROME (1-556): 1.77e-145: 435: 20.44
+	Hs
		261700 VAMP4_HUMAN (3-73): 1.13e-25: 95.3: 29.58		SCFD1_HUMAN (18-553): 2.28e-141: 425: 20.10
+	Hs
		263311 SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65		SCFD1_HUMAN (18-553): 2.28e-141: 425: 20.10
+	Sc
		605789 SNC2_YEAST (2-74): 6.15e-24: 90: 23.29		SLY1_YEAST (12-560): 9.85e-129: 393: 19.11
+	Sc
		605785 SNC1_YEAST (2-72): 1.48e-23: 89.2: 21.13		SLY1_YEAST (12-560): 9.85e-129: 393: 19.11
+	Sc
		675081 SNC2_YEAST (2-74): 6.15e-24: 90: 23.29		SEC1_YEAST (2-550): 1.09e-115: 361: 17.53
+	Sc
		675073 SNC1_YEAST (2-72): 1.48e-23: 89.2: 21.13		SEC1_YEAST (2-550): 1.09e-115: 361: 17.53
+	Hs
		263356 SC22B_HUMAN (2-86): 2.38e-23: 91.1: 17.65		VP33B_HUMAN (3-550): 1.22e-106: 334: 14.66
+	Tt
		101885 G0S5G3_CHATD (2-91): 1.45e-31: 113: 27.78		G0SCM5_CHATD (15-491): 1.47e-55: 202: 19.50