Interactor 1: KLHL2 (O95198)
Kelch-like protein 2 (Actin-binding protein Mayven)
Gene: KLHL2

Interactor 2: KLH12 (Q53G59)
Kelch-like protein 12 (CUL3-interacting protein 1) (DKIR homolog) (hDKIR)
Gene: KLHL12

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 16189514, 21516116, 28514442, 32296183, 33961781, 15383316, unassigned1304, 30190310
Identification Methods two hybrid, affinity chromatography technology, two hybrid array, validated two hybrid, two hybrid prey pooling approach, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains BACK~BTB, BTB~BTB, Kelch_1~Kelch_1
Common GO terms GO:0005829 - cytosol
GO:0031463 - Cul3-RING ubiquitin ligase complex
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 593
Hs

1 568
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024